Di-8-ANEPPS CAS: 157134-53-7
MF: C36H52N2O3S
MW: 592.87
A fast responding membrane potential dye.

Di-8-ANEPPS (CAS 157134-53-7)

Di-8-ANEPPS | CAS 157134-53-7 is rated 5.0 out of 5 by 1.
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Synonym: 4-(2-[6-(Dioctylamino)-2-naphthalenyl]ethenyl)-1-(3-sulfopropyl)pyridinium inner salt
Application: A fast responding membrane potential dye
CAS Number: 157134-53-7
Molecular Weight: 592.87
Molecular Formula: C36H52N2O3S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Di-8-ANEPPS is a fast-responding membrane potential dye. It is more suitable for long-term membrane potential studies than di-4-ANEPPS (sc-214872) because of its better retention in the outer leaflet of plasma membranes. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses.


References

Antic, S., and Zecevic, D., Optical signals from neurons with internally applied voltage-sensitive dyes. J. Neurosci. 15, 1392, (1995)

Physical State :
Solid
Solubility :
Soluble in water (sightly), DMSO, and ethanol.
Storage :
Store at 4° C
Fluoresence :
λex 498 nm, λem 713 nm in DMSO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
6508718
MDL Number :
MFCD03453608
SMILES :
CCCCCCCCN(CCCCCCCC)C1=CC2=C(C=C1)C=C(C=C2)/C=C/C3=CC=[N+](C=C3)CCCS(=O)(=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Di-8-ANEPPS, sc-214873, is a red solid.
Answered by: Chemical Support 4
Date published: 2018-04-21
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Rated 5 out of 5 by from Various publications cite the use of Di Various publications cite the use of Di-8-ANEPPS for long-term membrane potential studies. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses. -SCBT Publication Review
Date published: 2015-01-23
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