di(2-Hydroxy Atorvastatin-d5) Calcium Salt (CAS 265989-47-7)

Di(2-Hydroxy Atorvastatin-d5) Calcium Salt is a deuterium-labeled version of the active metabolite of atorvastatin and is utilized extensively in analytical research. This compound is particularly useful in mass spectrometry studies as an internal standard due to its deuterium labeling, which allows for precise tracking and quantification of the non-labeled form of the metabolite. Its applications include research on chemical kinetics, where it aids in the investigation of the absorption, distribution, metabolism, and excretion (ADME) of atorvastatin. The calcium salt form enhances the solubility of the compound, making it more amenable to various analytical techniques. Researchers also employ di(2-Hydroxy Atorvastatin-d5) Calcium Salt in the study of enzyme-substrate interactions, especially those involving the cytochrome P450 system, which is responsible for the metabolism of many compounds including statins. Additionally, the compound serves as a reference material when developing and validating new analytical methods for detecting and measuring statin metabolites in biological samples.