Molecular structure of Dextromethorphan Hydrobromide Monohydrate, CAS Number: 6700-34-1
Dextromethorphan Hydrobromide Monohydrate (CAS 6700-34-1)
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Application:
Dextromethorphan Hydrobromide Monohydrate is an anti-tussive drug
CAS Number:
6700-34-1
Purity:
≥98%
Molecular Weight:
370.32
Molecular Formula:
C18H25NO•HBr•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dextromethorphan Hydrobromide Monohydrate is widely employed in scientific research due to its action as an NMDA receptor antagonist, which allows scientists to study the role of these receptors in neuroplasticity and neurotransmission. It is also utilized as a tool to probe the cough reflex arc, aiding in the understanding of its regulatory mechanisms. In neuroscience, the compound is valuable for investigating glutamatergic pathways and their involvement in neurodegenerative conditions. Additionally, researchers use dextromethorphan hydrobromide monohydrate to explore its impact on sigma-1 receptors, which are implicated in the modulation of neural signaling and plasticity.
Dextromethorphan Hydrobromide Monohydrate (CAS 6700-34-1) References
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- Effect of cinacalcet hydrochloride, a new calcimimetic agent, on the pharmacokinetics of dextromethorphan: in vitro and clinical studies. | Nakashima, D., et al. 2007. J Clin Pharmacol. 47: 1311-9. PMID: 17652181
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- Altered CYP2C9 activity following modulation of CYP3A4 levels in human hepatocytes: an example of protein-protein interactions. | Ramsden, D., et al. 2014. Drug Metab Dispos. 42: 1940-6. PMID: 25157098
- Dextromethorphan/quinidine: a review of its use in adults with pseudobulbar affect. | Yang, LP. and Deeks, ED. 2015. Drugs. 75: 83-90. PMID: 25420446
- Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. | Marquard, J., et al. 2015. Nat Med. 21: 363-72. PMID: 25774850
- Correction: CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug. | Vogl, S., et al. 2015. PLoS One. 10: e0126329. PMID: 25875957
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- Effect of Omeprazole and Dextromethorphan on the Urinary Metabolic Ratio of Flurbiprofen. | Vogl, S., et al. 2016. Basic Clin Pharmacol Toxicol. 118: 496-8. PMID: 26617075
- Effect of one-year dextromethorphan/quinidine treatment on management of respiratory impairment in amyotrophic lateral sclerosis. | Sancho, J., et al. 2021. Respir Med. 186: 106536. PMID: 34260979
Inhibitor of:
NMDA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dextromethorphan Hydrobromide Monohydrate, 5 g | sc-211278 | 5 g | $68.00 |