Dextran Sulfate, Sodium Salt MW ~500,000 (CAS 9011-18-1)
See product citations (7)
Alternate Names:
Dextran Sulfate is also known as Dexnon.
CAS Number:
9011-18-1
Molecular Weight:
500000
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dextran Sulfate, Sodium Salt with a molecular weight (MW) of approximately 500,000 is a large, highly branched, and complex polysaccharide. This compound consists of a dextran backbone, which is a polymer of glucose, that has been modified with sulfate groups, giving it a strong negative charge. The sodium salt form facilitates its dissolution in water, enhancing its solubility. The high molecular weight suggests that the chains of glucose units are extensive, resulting in a sizeable and voluminous molecule. This characteristic, combined with its anionic nature due to the sulfate groups, makes it suitable for various applications in scientific research and biotechnological processes, where such properties are desirable.
Dextran Sulfate, Sodium Salt MW ~500,000 (CAS 9011-18-1) References
- Dextran sulfate inhibits E-selectin-mediated neutrophil adhesion to endotoxin-activated vascular endothelial cells. | Matsumiya, A., et al. 1999. Life Sci. 64: PL9-17. PMID: 10069494
- Cholesterol content of human serum lipoproteins obtained by dextran sulfate precipitation and by preparative ultracentrifugation. | KRITCHEVSKY, D., et al. 1963. Proc Soc Exp Biol Med. 112: 259-62. PMID: 14035854
- Interaction of fibrinogen with dextran sulfate. | SASAKI, S. and NOGUCHI, H. 1959. J Gen Physiol. 43: 1-12. PMID: 14441863
- A novel method for differentiating dextran sulfate from related sulfated polysaccharides. | Ludwig-Baxter, KG., et al. 1991. J Pharm Sci. 80: 655-60. PMID: 1941563
- Murine Colitis modeling using Dextran Sulfate Sodium (DSS). | Whittem, CG., et al. 2010. J Vis Exp.. PMID: 20087313
- Synthesis, characterization and antimicrobial activity of dextran stabilized silver nanoparticles in aqueous medium. | Bankura, KP., et al. 2012. Carbohydr Polym. 89: 1159-65. PMID: 24750927
- Poly(3,4-ethylenedioxythiophene):dextran sulfate (PEDOT:DS) - a highly processable conductive organic biopolymer. | Harman, DG., et al. 2015. Acta Biomater. 14: 33-42. PMID: 25484333
- Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. | Wahl, GM., et al. 1979. Proc Natl Acad Sci U S A. 76: 3683-7. PMID: 291033
- Formulation and evaluation of injectable dextran sulfate sodium nanoparticles as a potent antibacterial agent. | Madkhali, OA., et al. 2021. Sci Rep. 11: 9914. PMID: 33972626
- Non-coating method for non-adherent cell culture using high molecular weight dextran sulfate and bovine serum albumin. | Kikuchi, T., et al. 2021. J Biosci Bioeng. 132: 537-542. PMID: 34518107
- Nature of the interaction of dextran sulfate with low density lipoproteins of plasma. | Nishida, T. and Cogan, U. 1970. J Biol Chem. 245: 4689-97. PMID: 5456144
- The rate of nucleic acid annealing to cytological preparations is increased in the presence of dextran sulfate. | Lederman, LL., et al. 1981. Anal Biochem. 117: 158-63. PMID: 6172056
- Dextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. | Warnick, GR., et al. 1982. Clin Chem. 28: 1379-88. PMID: 7074948
Inhibitor of:
alpha-L-iduronidase, Arylsulfatase B, Baculovirus gp64, C1s, CD73, CHST5, CHST6, EG215895, HAPLN4, HPSE2_Hpse2, Influenza B NA, and SCARF (scavenger receptor class F).Activator of:
ATIII, bFGF, C1rb, C2, FGF-7, glypican-2, HS3ST6, IL-1β, Kininogen I, Reg IIIγ, Siglec-1, Sulf-2, and XIIα.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dextran Sulfate, Sodium Salt MW ~500,000, 10 g | sc-203917 | 10 g | $56.00 | |||
Dextran Sulfate, Sodium Salt MW ~500,000, 50 g | sc-203917A | 50 g | $163.00 | |||
Dextran Sulfate, Sodium Salt MW ~500,000, 100 g | sc-203917B | 100 g | $367.00 | |||
Dextran Sulfate, Sodium Salt MW ~500,000, 1 kg | sc-203917C | 1 kg | $3070.00 |