Dexmedetomidine-d4 L-tartrate (CAS 176721-04-3 (unlabeled))
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Dexmedetomidine-d4 L-tartrate, a deuterium-labeled version of dexmedetomidine, is often utilized in analytical chemistry as an internal standard for mass spectrometry. Its stable isotopic label makes it particularly useful in tracing the pathways and metabolites of dexmedetomidine in pharmacokinetic studies without the interference of naturally occurring isotopes. Researchers leverage this compound to dissect the alpha-2 adrenergic receptor′s response to agonists, as dexmedetomidine is known for its selective agonistic effects on this receptor. In industrial applications, dexmedetomidine-d4 L-tartrate can be employed in the quality control stages of manufacturing processes that require exacting measurements of anesthetic agents or related substances.
Dexmedetomidine-d4 L-tartrate (CAS 176721-04-3 (unlabeled)) References
- An improved ultra-high-performance liquid chromatography-tandem mass spectrometric method for the quantitation of dexmedetomidine in small volume of pediatric plasma. | Moorthy, GS., et al. 2019. Biomed Chromatogr. 33: e4487. PMID: 30664276
- Simultaneous detection of a panel of nine sedatives and metabolites in plasma from critically ill pediatric patients via UPLC-MS/MS. | Birabaharan, J., et al. 2022. J Pharm Biomed Anal. 218: 114853. PMID: 35659658
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dexmedetomidine-d4 L-tartrate, 1 mg | sc-499814 | 1 mg | $544.00 |