Desthiobiotin-PEG3-azide (CAS 1426828-06-9)
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Desthiobiotin-PEG3-Azide, also known as DBA, is a polyethylene glycol (PEG) derivative that is biotinylated and features an azide group at one end. This versatile reagent has found extensive use in various scientific research applications, including protein and DNA labeling, as well as serving as a substrate for enzyme assays. It is employed in bioconjugation reactions and functions as a linker molecule for synthesizing other bioconjugates. The highly reactive azide group within Desthiobiotin-PEG3-Azide facilitates the formation of covalent bonds with diverse molecules such as proteins, peptides, and carbohydrates. Through a nucleophilic substitution reaction, the azide group is replaced by the target molecule, resulting in the formation of a stable covalent bond between the two molecules.
Desthiobiotin-PEG3-azide (CAS 1426828-06-9) References
- Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. | Hahm, HS., et al. 2020. Nat Chem Biol. 16: 150-159. PMID: 31768034
- Intracellular vesicle clusters are organelles that synthesize extracellular vesicle-associated cargo proteins in yeast. | Winters, CM., et al. 2020. J Biol Chem. 295: 2650-2663. PMID: 31974164
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Desthiobiotin-PEG3-azide, 5 mg | sc-496162 | 5 mg | $317.00 |