Date published: 2026-1-9

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Desonide (CAS 638-94-8)

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Alternate Names:
(11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna -1,4-diene-3,20-dione; 16α-Hydroxyprednisolone Acetonide
Application:
Desonide is an antiinflammatory compound
CAS Number:
638-94-8
Purity:
≥99%
Molecular Weight:
416.51
Molecular Formula:
C24H32O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Desonide is an anti-inflammatory.


Desonide (CAS 638-94-8) References

  1. Influence of cyclodextrin complexation on the in vitro permeation and skin metabolism of dexamethasone.  |  Lopez, RF., et al. 2000. Int J Pharm. 200: 127-32. PMID: 10845694
  2. Comparison of the effects of a non-steroidal anti-inflammatory agent, an immunosuppressive, a corticosteroid and an immunomodulator on various immunological and non-immunological inflammatory experimental models.  |  Tarayre, JP. and Lauressergues, H. 1979. Arch Int Pharmacodyn Ther. 242: 159-76. PMID: 161700
  3. Preventive effects of multi-lamellar emulsion on low potency topical steroid induced local adverse effect.  |  Sul, GD., et al. 2013. Ann Dermatol. 25: 5-11. PMID: 23467730
  4. Desonide nanoencapsulation with açai oil as oil core: Physicochemical characterization, photostability study and in vitro phototoxicity evaluation.  |  Rosa, P., et al. 2019. J Photochem Photobiol B. 199: 111606. PMID: 31522112
  5. Comparison of the cutaneous/systemic antiinflammatory activity ratios for desonide and hydrocortisone in various experimental models.  |  Tarayre, JP., et al. 1988. Arzneimittelforschung. 38: 542-5. PMID: 3401268
  6. Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide.  |  Song, H., et al. 2022. Proc Natl Acad Sci U S A. 119: e2114303119. PMID: 35238684
  7. Calcium-Based Antimicrobial Peptide Compounds Attenuate DNFB-Induced Atopic Dermatitis-Like Skin Lesions via Th-Cells in BALB/c Mice.  |  Liu, Q., et al. 2022. Int J Mol Sci. 23: PMID: 36232673
  8. Comparison of the effect of phenylbutazone, desonide and cyclophosphamide on four types of experimental pleurisy.  |  Tarayre, JP. and Lauressergues, H. 1980. J Pharm Pharmacol. 32: 408-12. PMID: 6106673
  9. Modulation by various locally applied anti-inflammatory and anti-allergic compounds of the immune and non-immune inflammation induced by picryl chloride in mice.  |  Tarayre, JP. and Lauressergues, H. 1982. Agents Actions. 12: 662-70. PMID: 6187193
  10. Pharmacological comparison of the immune and non-immune inflammations induced by picryl chloride and oxazolone in mice.  |  Tarayre, JP., et al. 1984. Arch Int Pharmacodyn Ther. 269: 153-66. PMID: 6466004
  11. Pharmacological study of cantharidin-induced ear inflammation in mice.  |  Tarayre, JP., et al. 1984. J Pharmacol Methods. 11: 271-7. PMID: 6738082
  12. Enhanced percutaneous penetration with 1-dodecylazacycloheptan-2-one.  |  Stoughton, RB. 1982. Arch Dermatol. 118: 474-7. PMID: 7092271
  13. GLC analysis of hydrocortisone, triamcinolone acetonide, and desonide in culture media of mouse and human dermal fibroblasts using flame-ionization detection.  |  Au, DS., et al. 1981. J Pharm Sci. 70: 917-23. PMID: 7310664
  14. Corticosteroid-induced dermal atrophy in the rat.  |  Young, JM., et al. 1977. J Invest Dermatol. 69: 458-62. PMID: 908845

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Desonide, 10 mg

sc-211275
10 mg
$171.00