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Desmethyl Atomoxetine Hydrochloride (CAS 881995-46-6)

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Application:
Desmethyl Atomoxetine Hydrochloride is a metabolite of Tomoxetine
CAS Number:
881995-46-6
Molecular Weight:
277.79
Molecular Formula:
C16H20ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Desmethyl Atomoxetine Hydrochloride, a metabolite derivative of Atomoxetine, is pivotal in neuroscience research, particularly in the study of neurotransmitter regulation within the central nervous system. This compound uniquely inhibits the reuptake of norepinephrine, a critical neurotransmitter involved in numerous brain functions. The addition of hydrochloride to its structure enhances its solubility and stability, facilitating its use in experimental studies. Its ability to selectively act on norepinephrine reuptake pathways allows researchers to investigate the complexities of neurotransmitter dynamics and their impact on neural processes. This exploration contributes to a deeper understanding of neural function and behavior, emphasizing its significance in neuroscientific research. Through its application in various studies, Desmethyl Atomoxetine Hydrochloride aids in advancing our knowledge of the central nervous system, offering insights into the mechanisms that underpin neural communication and activity.


Desmethyl Atomoxetine Hydrochloride (CAS 881995-46-6) References

  1. Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication.  |  Wong, DT., et al. 1995. Life Sci. 57: 411-41. PMID: 7623609
  2. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells.  |  Beck, SG., et al. 1997. J Pharmacol Exp Ther. 281: 115-22. PMID: 9103487
  3. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites.  |  Owens, MJ., et al. 1997. J Pharmacol Exp Ther. 283: 1305-22. PMID: 9400006

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Desmethyl Atomoxetine Hydrochloride, 1 mg

sc-207537
1 mg
$306.00