Molecular structure of Desipramine-d3, CAS Number: 65100-49-4
Desipramine-d3 (CAS 65100-49-4)
Alternate Names:
10,11-Dihydro-N-(methyl-d3)-5H-dibenz[b,f]azepine-5-propanamine
CAS Number:
65100-49-4
Molecular Weight:
269.40
Molecular Formula:
C18H19D3N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Desipramine-d3 is a tricyclic antidepressant that functions by inhibiting the reuptake of norepinephrine and serotonin in the central nervous system. It is a deuterated form of desipramine, which means that some of the hydrogen atoms in the compound have been replaced with deuterium, a stable isotope of hydrogen. This labeling with deuterium allows for the use of desipramine-d3 in metabolic studies, as it can be distinguished from the non-labeled compound in biological systems. Desipramine-d3 is used as an internal standard in mass spectrometry-based assays to quantify desipramine levels in biological samples.
Desipramine-d3 (CAS 65100-49-4) References
- The effect of amitriptyline, desipramine and imipramine on the vivo brain synthesis of 3H-noradrenaline from 3H-L-dopa in the rat. | Nielsen, M., et al. 1975. Psychopharmacologia. 41: 249-54. PMID: 1098088
- Method validation of a tricyclic antidepressant drug panel in urine by UPLC-MS/MS. | Lin, CN., et al. 2014. Ann Clin Lab Sci. 44: 431-6. PMID: 25361928
- Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS). | Crutchfield, CA., et al. 2016. Methods Mol Biol. 1383: 265-70. PMID: 26660194
- Determination of Nicotine, Cotinine and Trans-3'-Hydroxycotinine using LC/MS/MS in Forensic Samples of a Nicotine Fatal Case by Oral Ingestion of e-cigarette Liquid. | You, G., et al. 2016. J Forensic Sci. 61: 1149-1154. PMID: 27238766
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Desipramine-d3, 2.5 mg | sc-207535 | 2.5 mg | $380.00 |