Date published: 2026-4-24

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Desipramine-2,4,6,8-d4 Hydrochloride (CAS 61361-34-0)

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Alternate Names:
10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine-d4; G-35020-d4; JB-8181-d4; NSc-114901-d4; Norpramin-d4
Application:
Desipramine-2,4,6,8-d4 Hydrochloride is a potent, labeled inhibitor of SLC6A2
CAS Number:
61361-34-0
Molecular Weight:
306.87
Molecular Formula:
C18H19D4ClN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Labelled tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.


Desipramine-2,4,6,8-d4 Hydrochloride (CAS 61361-34-0) References

  1. Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones.  |  Okugawa, G., et al. 1999. J Neuroendocrinol. 11: 887-95. PMID: 10520140
  2. Plasma membrane monoamine transporters: structure, regulation and function.  |  Torres, GE., et al. 2003. Nat Rev Neurosci. 4: 13-25. PMID: 12511858
  3. A pilot study of the mechanism of action of desipramine.  |  Checkley, SA., et al. 1981. Br J Psychiatry. 138: 248-51. PMID: 6268238
  4. Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine.  |  Zhu, MY., et al. 1998. J Neurochem. 70: 1547-55. PMID: 9523572

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Desipramine-2,4,6,8-d4 Hydrochloride, 1 mg

sc-218142
1 mg
$380.00