DEPMPO CAS: 157230-67-6
MF: C9H18NO4P
MW: 235.21
An efficient spin trap for detection of O-, N-, S- and C-centered radicals.

DEPMPO (CAS 157230-67-6)

DEPMPO | CAS 157230-67-6 is rated 5.0 out of 5 by 1.
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Alternate Names: 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide
Application: DEPMPO is an efficient spin trap for detection of O-, N-, S- and C-centered radicals
CAS Number: 157230-67-6
Purity: ≥99%
Molecular Weight: 235.21
Molecular Formula: C9H18NO4P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

DEPMPO is the most efficient spin trap for the in vitro detection of O-, N-, S- and C-centered free radicals. Has a longer life-time than DMPO. Can distinguish between superoxide-dependent and independent mechanisms that lead to the hydroxyl radical. Less lipophilic (Kp=0.16) than DIPPMPO.


References

1. Frejaville, C., et al. 1995. J. Med. Chem. 38: 258-265. PMID: 7830268
2. Karoui, H., et al. 1996. J. Biol. Chem. 271: 6000-6009. PMID: 8626383
3. Delmas-Beauvieux, M.C., et al. 1997. MAGMA. 5: 45-52. PMID: 9219179
4 .Muller, A., et al. 1997. Exp. Eye Res. 64: 637-643. PMID: 9227282
5. Roubaud, V., et al. 1997. Anal. Biochem. 247: 404-411. PMID: 9177705
6. Vásquez-Vivar, J., et al. 1997. FEBS Lett. 403: 127-130. PMID: 9042951
7. Roubaud, V., et al. 1998. Anal. Biochem. 257: 210-217. PMID: 9514781
8. Liu, K.J., et al. 1999. Free Radic. Biol. Med. 26: 714-721. PMID: 10218661
9. Stolze, K., et al. 2000. Free Radic. Biol. Med. 29: 1005-1014. PMID: 11084289
10. Dambrova, M., et al. 2000. Biochem. Biophys. Res. Commun. 275: 895-898. PMID: 10973818
11. Jackson, S.K., et al. 2002. Free Radic. Biol. Med. 32: 228-232. PMID: 11827748
12. Clement, J.L., et al. 2003. Org. Biomol. Chem. 1: 1591-1597. PMID: 12926292
13. Dikalov, S., et al. 2003. Free Radic. Res. 37: 705-712. PMID: 12911266

Appearance :
Oil
Physical State :
Liquid
Solubility :
Soluble in water (100 mg/ml), 100% ethanol, DMSO (10 mg/ml), dichloromethane, and methanol.
Storage :
Store at -80° C
Melting Point :
90.27° C (Predicted)
Boiling Point :
412.42° C at 760 mmHg (Predicted)
Density :
1.14 g/mL (Predicted)
Refractive Index :
n20D 1.47 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
119606
MDL Number :
MFCD01074976
SMILES :
CCOP(=O)(OCC)C1(C)CCC=[N+]1[O-]

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Certificate of Analysis

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DEPMPO (CAS 157230-67-6) Product Citations

See how others have used DEPMPO (CAS 157230-67-6). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 25058920  Xiao, Y. et al. 2014. Life Sci. 112: 33-40.

PMID: # 22149535  Hornyák, I. et al. 2012. Free Radic. Res. 46: 214-25.

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Various publications cite DEPMPO at the most Various publications cite DEPMPO at the most efficient spin trap for the in vitro detection of O-, N-, S- and C-centered free radicals. Has a longer life-time than DMPO. Can distinguish between superoxide-dependent and independent mechanisms that lead to the hydroxyl radical. Less lipophilic (Kp=0.16) than DIPPMPO. -SCBT Publication Review
Date published: 2015-04-29
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