Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
DENR (density-regulated protein), also designated DRP or smooth muscle cell-associated protein 3 (SMAP-3), is a 198 amino acid protein whose expression increases when cells are present in high densities. It has also been shown that DENR expression does not increase during growth arrest. DENR is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. DENR was also found at higher levels in cells expressing the neu proto-oncogene. DENR contains one SUI1 domain and interacts with MCTS1. The SUI1 domain contains sequence similarity to the budding yeast protein SUI1, which is a translation-initiation factor that directs the ribosome to the appropriate translation start site.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Hello! I'm interested in this antibody. Why is the band expected at ~28kd, but DENR is a 22kd protein?
Asked by: YLfhcrc
Thank you for your question. The predicted molecular weight of DENR is 22 kDa, however the observed molecular weight of the endogenous protein is ~27-31 kDa in the cell lines we have tested. The difference between the predicted and observed molecular weight may be due to post-translational modifications of the protein.
Answered by: Technical Support
Date published: 2019-03-10
For Western Blot, is it recommended to use denatured or non-denatured conditions with DENR (NQ-B8): sc-134315 antibody?
Asked by: Randy McDonald
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
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