Molecular structure of Deltamethrin, CAS Number: 52918-63-5
Deltamethrin (CAS 52918-63-5)
See product citations (8)
Application:
Deltamethrin is a Type II pyrethroid insecticide that potently inhibits calcineurin
CAS Number:
52918-63-5
Purity:
98%
Molecular Weight:
505.2
Molecular Formula:
C22H19Br2NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Deltamethrin is a synthetic compound that modulates sodium channels in the nerve cell membrane. This compound can keep the Na+ channels in an open state for a long time resulting to hyperactivity of the nervous system in mammals and insects. Deltamethrin can increase neurotransmitter release which is associated with elevated levels of intrasynaptosomal free Ca2+ and protein phosphorylation activities. Research shows that in the presence of increasing concentrations of deltamethrin, mRNA levels of IGF-I, IGF-II and GH-I significantly decreased in rainbow trout. Deltamethrin is an inhibitor of PP2.
Deltamethrin (CAS 52918-63-5) References
- Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides. | Enan, E. and Matsumura, F. 1992. Biochem Pharmacol. 43: 1777-84. PMID: 1315545
- Nerve membrane Na+ channels as targets of insecticides. | Narahashi, T. 1992. Trends Pharmacol Sci. 13: 236-41. PMID: 1321523
- Physiological prediction of muscle forces--I. Theoretical formulation. | Kaufman, KR., et al. 1991. Neuroscience. 40: 781-92. PMID: 2062441
- Acute and long-term genotoxicity of deltamethrin to insulin-like growth factors and growth hormone in rainbow trout. | Aksakal, E., et al. 2010. Comp Biochem Physiol C Toxicol Pharmacol. 152: 451-5. PMID: 20647053
- Effects of deltamethrin exposure on the cytochrome P450 monooxygenases of Aedes albopictus (Skuse) larvae from a dengue-endemic region of northern part of West Bengal, India. | Das, P., et al. 2024. Med Vet Entomol.. PMID: 38478926
- Innovative detection mechanism for deltamethrin based on a dual-emitting Fluoroprobe and its application in a smartphone-based photoelectric conversion device. | Li, Z., et al. 2024. Food Chem. 449: 139231. PMID: 38579654
- The Protective Effect of N-acetylcysteine against Deltamethrin-Induced Hepatotoxicity in Mice. | Ameri, A., et al. 2024. Avicenna J Med Biotechnol. 16: 88-94. PMID: 38618504
- Assessment of deltamethrin-induced DNA damage, neurotoxic and neuroimmune effects in the brain tissue of brown trout (Salmo trutta fario). | Karatas, T. and Cakir, M. 2024. Vet Med (Praha). 69: 77-83. PMID: 38623154
- Contribution of Immune Responses to the Cardiotoxicity and Hepatotoxicity of Deltamethrin in Early Life Stage Zebrafish (Danio rerio). | Wang, J., et al. 2024. Environ Sci Technol. 58: 9515-9524. PMID: 38687472
- Potential of MALDI-TOF MS biotyping to detect deltamethrin resistance in the dengue vector Aedes aegypti. | Almeras, L., et al. 2024. PLoS One. 19: e0303027. PMID: 38728353
- Isolation, characterization and functional analysis of a bacteriophage targeting Culex pipiens pallens resistance-associated Aeromonas hydrophila. | Li, J., et al. 2024. Parasit Vectors. 17: 222. PMID: 38745242
- Pyrethroid resistance and gene expression profile of a new resistant An. gambiae colony from Uganda reveals multiple resistance mechanisms and overexpression of Glutathione-S-Transferases linked to survival of PBO-pyrethroid combination. | Oruni, A., et al. 2024. Wellcome Open Res. 9: 13. PMID: 38813466
- Activation of phosphoinositide/protein kinase C pathway in rat brain tissue by pyrethroids. | Enan, E. and Matsumura, F. 1993. Biochem Pharmacol. 45: 703-10. PMID: 8095139
Inhibitor of:
PP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Deltamethrin, 10 mg | sc-24013 | 10 mg | $62.00 | |||
Deltamethrin, 50 mg | sc-24013A | 50 mg | $259.00 |