Molecular structure of Dehydroacetic acid, CAS Number: 520-45-6
Dehydroacetic acid (CAS 520-45-6)
Alternate Names:
3-Acetyl-4-hydroxy-6-methyl-2-pyrone
CAS Number:
520-45-6
Molecular Weight:
168.15
Molecular Formula:
C8H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Dehydroacetic acid (DHA) is a colorless, and odorless compound that is soluble in water. Dehydroacetic acid operates as an antimicrobial agent by disrupting the cell membrane of microorganisms. It achieves this by binding to the phospholipid head groups within the cell membrane, thereby compromising its integrity and resulting in cell death. Additionally, Dehydroacetic acid has demonstrated inhibitory effects on specific enzymes such as DNA polymerase and RNA polymerase, which play critical roles in bacterial cell replication.
Dehydroacetic acid (CAS 520-45-6) References
- Dehydroacetic acid (DHA). Estimation, absorption and distribution. | WOODS, LA., et al. 1950. J Pharmacol Exp Ther. 99: 84-97. PMID: 15429019
- Dehydroacetic acid sodium salt stability in cosmetic preservative mixtures. | Bennassi, CA., et al. 1988. Int J Cosmet Sci. 10: 29-32. PMID: 19456908
- Absolute quantification of dehydroacetic acid in processed foods using quantitative ¹H NMR. | Ohtsuki, T., et al. 2013. Food Chem. 141: 1322-7. PMID: 23790920
- [Analysis of the reaction solution for dehydroacetic acid by ethyl acetoacetate using high formance liquid chromatography]. | Chen, Q., et al. 2013. Se Pu. 31: 462-6. PMID: 24010347
- [Identification of benzoic acid, sorbic aicid and dehydroacetic acid residues in alcoholic drinks and beverages]. | Zhu, H., et al. 2014. Wei Sheng Yan Jiu. 43: 116-20. PMID: 24564123
- Analogues of Dehydroacetic Acid as Selective and Potent Agonists of an Ectopic Odorant Receptor through a Combination of Hydrophilic and Hydrophobic Interactions. | Park, BB., et al. 2017. ChemMedChem. 12: 477-482. PMID: 28296270
- Dehydroacetic Acid Derivatives Bearing Amide or Urea Moieties as Effective Anion Receptors. | Bregović, N., et al. 2017. Chemistry. 23: 10396-10406. PMID: 28493492
- Dehydroacetic acid in cheese and cheese coating, results of official control in Italy. | Scordino, M., et al. 2018. Food Addit Contam Part B Surveill. 11: 75-81. PMID: 29228873
- Photoreactivities of the Antiseptics Dehydroacetic Acid and Sodium Dehydroacetate Used in Cosmetics. | Izawa, T., et al. 2018. Chem Pharm Bull (Tokyo). 66: 581-584. PMID: 29467339
- Ultraviolet-visible phototransformation of dehydroacetic acid - Structural characterization of photoproducts and global ecotoxicity. | De Vaugelade, S., et al. 2018. Rapid Commun Mass Spectrom. 32: 862-870. PMID: 29520993
- Modification of insulin amyloid aggregation by Zr phthalocyanines functionalized with dehydroacetic acid derivatives. | Chernii, S., et al. 2021. PLoS One. 16: e0243904. PMID: 33411832
- Synthesis of Pogostone-Inspired Dehydroacetic Acid Derivatives and Their Antifungal Activity against Sclerotinia sclerotiorum (Lib.) de Bary. | Wang, D., et al. 2023. Chem Biodivers. 20: e202300128. PMID: 37148476
- Simultaneous determination of dehydroacetic acid, benzoic acid, sorbic acid, methylparaben and ethylparaben in foods by high-performance liquid chromatography. | So, JS., et al. 2023. Food Sci Biotechnol. 32: 1173-1183. PMID: 37362818
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NDUFA6.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dehydroacetic acid, 100 g | sc-239657 | 100 g | $52.00 |