Molecular structure of Dehydro Nifedipine, CAS Number: 67035-22-7
Dehydro Nifedipine (CAS 67035-22-7)
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Alternate Names:
Oxidized Nifedipine; Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
Application:
Dehydro Nifedipine is a main Nifedipine metabolite in human plasma
CAS Number:
67035-22-7
Molecular Weight:
344.32
Molecular Formula:
C17H16N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Dehydro Nifedipine is the main Nifedipine metabolite in human plasma. Dehydro nifedipine is a compound that is generated through the metabolism of nifedipine by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. This metabolite has been observed to inhibit glucose uptake in PC-12 cells, with an IC50 value of 130 μM. Structurally, dehydro nifedipine falls into the phenylpyridine class of organic compounds, characterized by polycyclic aromatic structures comprising a benzene ring connected to a pyridine ring via a CC or CN bond. It is considered to be a relatively neutral molecule with limited solubility in water.
Dehydro Nifedipine (CAS 67035-22-7) References
- Synthetic organic compounds and their transformation products in groundwater: occurrence, fate and mitigation. | Postigo, C. and Barceló, D. 2015. Sci Total Environ. 503-504: 32-47. PMID: 24974362
- The development of a functional human small intestinal epithelium model for drug absorption. | Kwon, O., et al. 2021. Sci Adv. 7: PMID: 34078609
- Investigation of nifedipine absorption in different regions of the human gastrointestinal (GI) tract after simultaneous administration of 13C- and 12C-nifedipine. | Bode, H., et al. 1996. Eur J Clin Pharmacol. 50: 195-201. PMID: 8737759
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dehydro Nifedipine, 2 mg | sc-211226A | 2 mg | $265.00 | |||
Dehydro Nifedipine, 5 mg | sc-211226 | 5 mg | $302.00 | |||
Dehydro Nifedipine, 10 mg | sc-211226B | 10 mg | $627.00 | |||
Dehydro Nifedipine, 25 mg | sc-211226C | 25 mg | $1469.00 | |||
Dehydro Nifedipine, 50 mg | sc-211226D | 50 mg | $2448.00 |