![Decyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate - chemical structure image](https://media.scbt.com/product/decyl-2-1-2-bromoacetyl-3-oxo-2-piperazinyl-acetate-structure_23_99_b_239926.jpg)
![Decyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate - chemical structure image](https://media.scbt.com/product/decyl-2-1-2-bromoacetyl-3-oxo-2-piperazinyl-acetate-structure_23_99_t_239926.jpg "Molecular structure of Decyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate")
Decyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate
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Mizoribine is an imidazole nucleoside immunosuppressant agent that was first isolated from the mold Eupenicillium brefeldimium with antibiotic and cytotoxic effects. In a mouse model for IgA nephropathy, Mizoribine was documented to influence the proliferation of B cells and decrease the glomerular IgA load while increasing glomerular expansion. In addition in human B cells the compound has been observed to Inhibit the expression of cyclin A. The immunosuppressive effects of Mizoribine Hydrobromide also effects T cells through suppression of G to S phase transition. In the case of puromycin aminonucleoside nephropathy Mizoribine demonstrated the ability to prevent podocyte injury. The compound has also been documented to induce the differentiation of promyelocytes on a mechansim relying on impaired guanine nucleotide synthesis. It belongs to the class of purine analogues and acts as an immunosuppressant.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Decyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate, 500 mg | sc-326755 | 500 mg | $284.00 |