Deacetyl Diltiazem N-Oxide (CAS 122619-90-3)
Alternate Names:
(2S,3S)-5-[2-(Dimethyloxidoamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one; (2S-cis)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro- 3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one N-Oxide
CAS Number:
122619-90-3
Molecular Weight:
388.48
Molecular Formula:
C20H24N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Deacetyl Diltiazem N-Oxide binds to the same receptors as diltiazem, and is thought to act as an agonist at these receptors. This means that Deacetyl Diltiazem N-Oxide can activate the same pathways as diltiazem, leading to the same biochemical and physiological effects. N-Oxides are known for their ability to participate in a variety of chemical reactions, including redox reactions, which can be useful in synthetic chemistry and the study of biochemical pathways. The process of deacetylation, removing an acetyl group, further alters the compound′s properties by changing its molecular weight, hydrophobicity, and possibly its ability to cross biological membranes.
Deacetyl Diltiazem N-Oxide (CAS 122619-90-3) References
- Simple and sensitive high-performance liquid chromatographic method for the determination of diltiazem and six of its metabolites in human plasma. | Hussain, MD., et al. 1992. J Chromatogr. 582: 203-9. PMID: 1491042
- Effect of diltiazem and its metabolites on the uptake of adenosine in blood: an in-vitro investigation. | Yeung, PK., et al. 1991. J Pharm Pharmacol. 43: 685-9. PMID: 1682442
- Pharmacokinetics and metabolism of diltiazem in rabbits after a single intravenous or single oral administration. | Yeung, PK., et al. 1991. Eur J Drug Metab Pharmacokinet. 16: 69-74. PMID: 1936064
- High-performance liquid chromatographic assay of diltiazem and six of its metabolites in plasma: application to a pharmacokinetic study in healthy volunteers. | Yeung, PK., et al. 1989. J Pharm Sci. 78: 592-7. PMID: 2778663
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Deacetyl Diltiazem N-Oxide, 5 mg | sc-470939 | 5 mg | $367.00 |