Molecular structure of DEA, CAS Number: 150314-35-5
DEA (CAS 150314-35-5)
Alternate Names:
Docosatetraenylethanolamide
Application:
DEA is an endocannabinoid agonist of the CB1 receptor
CAS Number:
150314-35-5
Molecular Weight:
375.59
Molecular Formula:
C24H41NO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
DEA is a potent endocannabinoid (anandamide analog) that activates CB1 receptors in microglia and binds to rat synaptosomal membranes (KI = 34.4 nM). Cannabimimetic.
DEA (CAS 150314-35-5) References
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- Nonpsychotropic cannabinoid receptors regulate microglial cell migration. | Walter, L., et al. 2003. J Neurosci. 23: 1398-405. PMID: 12598628
- Similar in vitro pharmacology of human cannabinoid CB1 receptor variants expressed in CHO cells. | Xiao, JC., et al. 2008. Brain Res. 1238: 36-43. PMID: 18761332
- Critical role of the endocannabinoid system in the regulation of food intake and energy metabolism, with phylogenetic, developmental, and pathophysiological implications. | Viveros, MP., et al. 2008. Endocr Metab Immune Disord Drug Targets. 8: 220-30. PMID: 18782018
- Antitumorigenic effects of cannabinoids beyond apoptosis. | Freimuth, N., et al. 2010. J Pharmacol Exp Ther. 332: 336-44. PMID: 19889794
- Simultaneous Quantification of Anandamide and Other Endocannabinoids in Dorsal Vagal Complex of Rat Brainstem by LC-MS. | Chen, J., et al. 2009. Chromatographia. 69: 1-7. PMID: 20046895
- The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning? | Bermudez-Silva, FJ., et al. 2010. Pharmacol Biochem Behav. 95: 375-82. PMID: 20347862
- Update on the endocannabinoid system as an anticancer target. | Malfitano, AM., et al. 2011. Expert Opin Ther Targets. 15: 297-308. PMID: 21244344
- The differential effect of CB1 receptors on the discharge of afferent and efferent fibres supplying the rat jejunum. | Donovan, J. and Grundy, D. 2011. Neurogastroenterol Motil. 23: 567-e209. PMID: 21414102
- Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson's Disease. | Kelly, R., et al. 2020. Molecules. 25: PMID: 31973235
- Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. | Hanus, L., et al. 1993. J Med Chem. 36: 3032-4. PMID: 8411021
- Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides. | Barg, J., et al. 1995. Eur J Pharmacol. 287: 145-52. PMID: 8749028
Activator of:
CB1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DEA, 5 mg | sc-203024 | 5 mg | $57.00 |