Molecular structure of DBCO-PEG(4)-NH2, CAS Number: 1255942-08-5
DBCO-PEG(4)-NH2 (CAS 1255942-08-5)
Alternate Names:
Azadibenzocyclooctyne-PEG4 amine; DBCO-PEG(4)-amine
CAS Number:
1255942-08-5
Molecular Weight:
523.62
Molecular Formula:
C29H37N3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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DBCO-PEG(4)-NH2 is a versatile compound used in chemical synthesis as a carboxyl-reactive building block. It possesses an extended PEG spacer arm, which enhances its water solubility. When combined with activators like EDC or DCC, this reagent facilitates the derivatization of carboxyl groups or activated esters, such as the NHS ester, through the formation of stable amide bonds. Its compatibility with various activation methods makes it useful for modifying and functionalizing molecules with carboxyl functionalities.
DBCO-PEG(4)-NH2 (CAS 1255942-08-5) References
- Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms. | Dennler, P., et al. 2015. Chembiochem. 16: 861-7. PMID: 25688874
- Click-crosslinkable and photodegradable gelatin hydrogels for cytocompatible optical cell manipulation in natural environment. | Tamura, M., et al. 2015. Sci Rep. 5: 15060. PMID: 26450015
- Molecular imaging of activated platelets via antibody-targeted ultra-small iron oxide nanoparticles displaying unique dual MRI contrast. | Ta, HT., et al. 2017. Biomaterials. 134: 31-42. PMID: 28453956
- Self-assembled thermoresponsive nanostructures of hyaluronic acid conjugates for osteoarthritis therapy. | Maudens, P., et al. 2018. Nanoscale. 10: 1845-1854. PMID: 29308811
- Next generation calmodulin affinity purification: Clickable calmodulin facilitates improved protein purification. | Fraseur, JG. and Kinzer-Ursem, TL. 2018. PLoS One. 13: e0197120. PMID: 29864125
- Living functional hydrogels generated by bioorthogonal cross-linking reactions of azide-modified cells with alkyne-modified polymers. | Nagahama, K., et al. 2018. Nat Commun. 9: 2195. PMID: 29875358
- Development of Biocompatible HA Hydrogels Embedded with a New Synthetic Peptide Promoting Cellular Migration for Advanced Wound Care Management. | Wang, SY., et al. 2018. Adv Sci (Weinh). 5: 1800852. PMID: 30479928
- Noninvasive PET tracking of post-transplant gut microbiota in living mice. | Wang, Y., et al. 2020. Eur J Nucl Med Mol Imaging. 47: 991-1002. PMID: 31897587
- Microfluidic Fabrication of Click Chemistry-Mediated Hyaluronic Acid Microgels: A Bottom-Up Material Guide to Tailor a Microgel's Physicochemical and Mechanical Properties. | Heida, T., et al. 2020. Polymers (Basel). 12: PMID: 32781609
- Diversification of polyphosphate end-labeling via bridging molecules. | Baker, CJ., et al. 2020. PLoS One. 15: e0237849. PMID: 32822431
- HSymM-guided engineering of the immunodominant p53 transactivation domain putative peptide antigen for improved binding to its anti-p53 monoclonal antibody. | Fritz, ZR., et al. 2021. Bioorg Med Chem Lett. 51: 128341. PMID: 34454062
- Thin Layer-Protected Gold Nanoparticles for Targeted Multimodal Imaging with Photoacoustic and CT. | Chen, J., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34832857
- Addition of Lauryldimethylamine N-Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes. | Bautista, L., et al. 2022. ACS Omega. 7: 34921-34928. PMID: 36211053
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DBCO-PEG(4)-NH2, 25 mg | sc-506569 | 25 mg | $339.00 |