Daudi Cell Lysate: sc-2415

Daudi cell lysate, derived from the Daudi cell linea human Burkitt's lymphoma modelis extensively used in immunology and cancer research to study B-cell functions and the mechanisms of lymphomagenesis. This lysate provides valuable insights into the molecular pathways that drive lymphoma cell survival, proliferation, and interaction with the immune system. Researchers utilize Daudi lysate to explore key signaling pathways like NF-κB and PI3K/Akt, which are crucial for cell survival and are often dysregulated in lymphoma. Additionally, this lysate is instrumental in studying the role of apoptosis regulators, such as Bcl-2 and caspases, in lymphoma pathophysiology. It also aids in the examination of antigen presentation capabilities and the response of lymphoma cells to various cytokines, contributing to our understanding of immune evasion strategies employed by malignant cells. The use of Daudi cell lysate in these studies helps delineate the complex biology of lymphoma cells, providing a basis for further research into the cellular and molecular mechanisms of B-cell lymphomas. By focusing on these fundamental aspects, Daudi cell lysate contributes significantly to the field of cancer biology.

Daudi Cell Lysate References:

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2. Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.  |  Xie, S., et al. 2002. Cell Cycle. 1: 424-9. PMID: 12548019
3. Lipid raft-associated protein sorting in exosomes.  |  de Gassart, A., et al. 2003. Blood. 102: 4336-44. PMID: 12881314
4. Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt′s lymphoma cells.  |  Fisch, P., et al. 1990. Science. 250: 1269-73. PMID: 1978758
5. Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens.  |  Ploegh, HL., et al. 1979. Proc Natl Acad Sci U S A. 76: 2273-7. PMID: 287067
6. Increased resistance to non-MHC-restricted cytotoxicity related to HLA A, B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells.  |  Quillet, A., et al. 1988. J Immunol. 141: 17-20. PMID: 3288697
7. Immunoglobulin synthesis and secretion. VI. Synthesis and intracellular transport of immunoglobulin in nonsecretory lymphoma cells.  |  Sherr, CJ. and Uhr, JW. 1971. J Exp Med. 133: 901-20. PMID: 5547061
8. Tunicamycin inhibits the expression of membrane IgM in the human lymphoblastoid cell line Daudi.  |  Kubo, RT. and Pelanne, ML. 1983. Mol Immunol. 20: 67-76. PMID: 6406840
9. Secretion of human immunoglobulins by mouse myeloma x Daudi somatic cell hybrids.  |  Erikson, J. and Croce, CM. 1982. Eur J Immunol. 12: 697-701. PMID: 6754388
10. Role of interferon alpha/beta receptor chain 1 in the structure and transmembrane signaling of the interferon alpha/beta receptor complex.  |  Constantinescu, SN., et al. 1994. Proc Natl Acad Sci U S A. 91: 9602-6. PMID: 7524081
11. Evidence that the Wiskott-Aldrich syndrome protein may be involved in lymphoid cell signaling pathways.  |  Cory, GO., et al. 1996. J Immunol. 157: 3791-5. PMID: 8892607
12. Alterations in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible associations with cytochrome P450 metabolism and increased protein tyrosine phosphorylation.  |  Mounho, BJ. and Burchiel, SW. 1998. Toxicol Appl Pharmacol. 149: 80-9. PMID: 9512730
13. Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol.  |  Salas, VM. and Burchiel, SW. 1998. Toxicol Appl Pharmacol. 151: 367-76. PMID: 9707513