Daoy Whole Cell Lysate: sc-364381

Daoy whole cell lysate is derived from the Daoy cell line, a human medulloblastoma model widely used in neuro-oncology research to study the molecular and cellular underpinnings of brain tumors. This lysate is particularly valuable for examining signaling pathways implicated in the development and progression of medulloblastoma, such as the Hedgehog (Hh) pathway, which is aberrantly activated in a subset of these tumors. Researchers utilize Daoy lysate to investigate the effects of pathway modulation on cell proliferation, differentiation, and apoptosis. It is also used to study gene expression profiles, protein-protein interactions, and the efficacy of potential inhibitors of the Hh pathway. The insights gained from such studies help in understanding the complex biology of medulloblastoma, focusing on the mechanisms that drive tumor growth and maintenance. Additionally, the lysate aids in exploring resistance mechanisms to targeted therapies, providing a foundation for developing more effective research tools. By utilizing Daoy whole cell lysate, scientists advance our fundamental knowledge of tumor biology, contributing significantly to the field of cancer research.