Date published: 2025-11-15

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Dansyl-L-valine (CAS 1098-50-6)

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Alternate Names:
5-Dimethylaminonaphthalene-1-sulfonyl-L-valine
CAS Number:
1098-50-6
Molecular Weight:
350.43
Molecular Formula:
C17H22N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Dansyl-L-valine, a derivative of L-valine, is a fluorescent compound extensively employed in diverse biochemical and physiological investigations. It serves as a valuable instrument for researchers, facilitating the measurement of various parameters such as protein-protein interactions, enzyme kinetics, and protein-ligand binding. Moreover, Dansyl-L-valine finds application in cell imaging, particularly in fluorescence microscopy. In scientific research, this compound is employed for assessing protein-protein interactions, enzyme kinetics, and protein-ligand binding in biochemical and physiological experiments. It also plays a role in cell imaging techniques like fluorescence microscopy. Additionally, Dansyl-L-valine possesses a mechanism of action centered around its capability to form a fluorescent complex with specific molecules. The formation of this complex occurs when the dansyl group binds to a particular target molecule. Consequently, this binding interaction induces fluorescence in the dansyl group, generating a detectable fluorescent signal. This signal can then be exploited to identify and quantify the activity of the target molecule.


Dansyl-L-valine (CAS 1098-50-6) References

  1. Pharmacokinetic characterization in xenografted mice of a series of first-generation mimics for HLA-DR antibody, Lym-1, as carrier molecules to image and treat lymphoma.  |  DeNardo, GL., et al. 2007. J Nucl Med. 48: 1338-47. PMID: 17631545
  2. Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin.  |  Ryan, AJ., et al. 2011. J Struct Biol. 174: 84-91. PMID: 20940056
  3. Fluorescence of dansyl amino acids in organic solvents and protein solutions  |  Raymond F. Chen. 1967. Archives of Biochemistry and Biophysics. 120: 609-620.
  4. Salinamides, Antiinflammatory Depsipeptides from a Marine Streptomycete  |  Bradley S. Moore, Jacqueline A. Trischman, Dieter Seng, David Kho, Paul R. Jensen, and William Fenical. 1999. J. Org. Chem. 64: 1145–1150.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Dansyl-L-valine, 1 g

sc-487076
1 g
$247.00