Molecular structure of D-Sorbitol, CAS Number: 50-70-4
D-Sorbitol (CAS 50-70-4)
Alternate Names:
D-Glucitol
Application:
D-Sorbitol is a sugar alcohol produced by the reduction of glucose
CAS Number:
50-70-4
Purity:
≥95%
Molecular Weight:
182.17
Molecular Formula:
C6H14O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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D-Sorbitol is a sugar alcohol produced by reduction of glucose. The compound is a polyol found in fruits such as apples, prunes, peaches, and pears. Although produced for varying uses synthetically the D-Sorbitol has been observed to be produced by the bacterium Zymomonas mobilis from glucose with the use of glucose-fructose oxidoreductase. Metabolism of D-Sorbitol has been found to generate superoxide anion radicals in mitochondria.
D-Sorbitol (CAS 50-70-4) References
- Sorbitol can be produced not only chemically but also biotechnologically. | Jonas, R. and Silveira, MM. 2004. Appl Biochem Biotechnol. 118: 321-36. PMID: 15304760
- Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications. | Obrosova, IG. 2005. Antioxid Redox Signal. 7: 1543-52. PMID: 16356118
- Humectancies of d-tagatose and d-sorbitol. | Lu, Y. 2001. Int J Cosmet Sci. 23: 175-81. PMID: 18498471
- Sorbitol dehydrogenase of Aspergillus niger, SdhA, is part of the oxido-reductive D-galactose pathway and essential for D-sorbitol catabolism. | Koivistoinen, OM., et al. 2012. FEBS Lett. 586: 378-83. PMID: 22245674
- D-sorbitol-induced phase control of TiO2 nanoparticles and its application for dye-sensitized solar cells. | Shaikh, SF., et al. 2016. Sci Rep. 6: 20103. PMID: 26857963
- Evaluation of in vivo efficacy of radiofrequency ablation with D-sorbitol in animal liver. | Morishita, A., et al. 2016. Mol Clin Oncol. 4: 183-186. PMID: 26893857
- Crystallization and Properties of NAD-Dependent D-Sorbitol Dehydrogenase from Gluconobacter suboxydans IFO 3257. | Adachi, O., et al. 1999. Biosci Biotechnol Biochem. 63: 1589-95. PMID: 27389646
- From D-sorbitol to five-membered bis(cyclo-carbonate) as a platform molecule for the synthesis of different original biobased chemicals and polymers. | Furtwengler, P. and Avérous, L. 2018. Sci Rep. 8: 9134. PMID: 29904097
- Crystal nucleation rates in glass-forming molecular liquids: D-sorbitol, D-arabitol, D-xylitol, and glycerol. | Huang, C., et al. 2018. J Chem Phys. 149: 054503. PMID: 30089376
- Overcoming NADPH product inhibition improves D-sorbitol conversion to L-sorbose. | Kim, TS., et al. 2019. Sci Rep. 9: 815. PMID: 30692560
- Addition Of D-Sorbitol Improves The Usability Of Ophthalmic Viscosurgical Devices. | Watanabe, I., et al. 2019. Clin Ophthalmol. 13: 1877-1885. PMID: 31576103
- D-sorbitol can keep the viscosity of dispersive ophthalmic viscosurgical device at room temperature for long term. | Nogami, E., et al. 2019. Sci Rep. 9: 16815. PMID: 31727999
- Elucidation of the Nature of Structural Relaxation in Glassy d-Sorbitol. | Krynski, M., et al. 2020. J Phys Chem B. 124: 1833-1838. PMID: 32017567
- D-Sorbitol Physical Properties Effects on Filaments Used by 3D Printing Process for Personalized Medicine. | Roulon, S., et al. 2021. Molecules. 26: PMID: 34070087
- Structures of glass-forming liquids by x-ray scattering: Glycerol, xylitol, and D-sorbitol. | Chen, Z., et al. 2021. J Chem Phys. 155: 244508. PMID: 34972382
Inhibitor of:
γN-crystallin, λ-crystallin, ζ-crystallin, GAL4 (DBD), Ketohexokinase, Sln1, and Transaldolase.Activator of:
APPBP1, BC030867, CD-MPR, claudin-3, G3BP1, GAL3ST2, GBP11, GK1, GLCNE, Hog1, HTLV-1 Tax, HXK I, IKKα, IKKβ, JIP-2, JIP-3, JNK2, JNK3, Klkb22, LZK, MEK kinase-4, MEK2, MEK3, Mindin, Mkk1, Mkk2, Mpk1, Msn2, Myo-inositol oxygenase, NFAT5, NFAT5a, NFAT5b, NFAT5c, OmpU, OSM, OXSR1, PAC-1, PIPK II β, plexin-C1, Pma2, Ribosomal Protein S6, rolled, SAPK4, Sho1, Sin4p, SSK1, Ste11, TAB1, TC 21, TEX33, Tra-1, Trk1, WNK1, and ZPK.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Sorbitol, 100 g | sc-203278A | 100 g | $28.00 | |||
D-Sorbitol, 1 kg | sc-203278 | 1 kg | $68.00 |