Molecular structure of D-Serine ethyl ester hydrochloride, CAS Number: 104055-46-1
D-Serine ethyl ester hydrochloride (CAS 104055-46-1)
Alternate Names:
D-Ser-OEt⋅HCl; D-β-Hydroxyalanine ethyl ester hydrochloride
Application:
D-Serine ethyl ester hydrochloride is a modulator of NMDA receptors
CAS Number:
104055-46-1
Purity:
≥99%
Molecular Weight:
169.61
Molecular Formula:
C5H11NO3·HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-Serine ethyl ester hydrochloride has been used to study spinocerebellar ataxia in murine models. It exhibits stereospecific modulation of N-methyl-d-aspartate (NMDA) type glutamate receptors, which appears to reduce ataxia-related falling in a dose-dependent manner.
D-Serine ethyl ester hydrochloride (CAS 104055-46-1) References
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- Azotides as Modular Peptide-Based Ligands for Asymmetric Lewis Acid Catalysis. | Jacobsen, CB., et al. 2019. J Org Chem. 84: 6940-6945. PMID: 31033291
- Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. | Liu, L., et al. 2021. J Med Chem. 64: 8391-8409. PMID: 34115499
- Discovery of benzo[d]isothiazole derivatives as novel scaffold inhibitors targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction through 'ring fusion' strategy. | Gao, Y., et al. 2022. Bioorg Chem. 123: 105769. PMID: 35405572
- Synthesis and Anti-Inflammatory Activity of the Natural Cyclooxygenase-2 Inhibitor Axinelline A and Its Analogues. | Ju, Z., et al. 2023. J Nat Prod. 86: 958-965. PMID: 36880830
- Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway. | Zhang, LQ., et al. 2023. Bioorg Med Chem. 94: 117478. PMID: 37742398
- The stereo-specific effect of D-serine ethylester and the D-cycloserine in ataxic mutant mice. | Saigoh, K., et al. 1998. Brain Res. 808: 42-7. PMID: 9795125
- First Asymmetric Total Synthesis of Salinosporamides D and I Using Memory of Chirality and Dynamic Kinetic Resolution | Park, S., Jeong, Y., Lim, C., & Kim, S. 2023. European Journal of Organic Chemistry. 26(39): e202300774.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Serine ethyl ester hydrochloride, 5 g | sc-294259 | 5 g | $83.00 | |||
D-Serine ethyl ester hydrochloride, 25 g | sc-294259A | 25 g | $290.00 |