Molecular structure of d-ribo Phytosphingosine 1-Phosphate, CAS Number: 38597-28-3
d-ribo Phytosphingosine 1-Phosphate (CAS 38597-28-3)
Alternate Names:
(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol 1-(Dihydrogen Phosphate); 4-D-Hydroxysphinganine 1-Phosphate; Methanol
Application:
d-ribo Phytosphingosine 1-Phosphate is a high affinity ligand for the S1P4/Edg-6 receptor
CAS Number:
38597-28-3
Molecular Weight:
397.49
Molecular Formula:
C18H40NO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
d-ribo Phytosphingosine 1-Phosphate is a potential modulator of cellular processes. It is also a high affinity ligand for the S1P4/Edg-6 receptor. d-ribo Phytosphingosine 1-Phosphate exerts its biological effects by binding to specific receptors on the cell surface, known as S1P receptors. There are five known S1P receptors, namely S1P1-5. Phytosphingosine 1-phosphate has been found to bind to S1P1 and S1P3 receptors, which are involved in cell migration, proliferation, and survival. The binding of Phytosphingosine 1-phosphate to S1P receptors activates downstream signaling pathways, which regulate various cellular processes.
d-ribo Phytosphingosine 1-Phosphate (CAS 38597-28-3) References
- Pharmacological characterization of human S1P4 using a novel radioligand, [4,5-3H]-dihydrosphingosine-1-phosphate. | Fossetta, J., et al. 2004. Br J Pharmacol. 142: 851-60. PMID: 15197107
- Synthesis of l-lyxo-phytosphingosine and its 1-phosphonate analogue using a threitol acetal synthon. | Lu, X., et al. 2004. J Org Chem. 69: 5433-8. PMID: 15287793
- An efficient preparation of isosteric phosphonate analogues of sphingolipids by opening of oxirane and cyclic sulfamidate intermediates with alpha-lithiated alkylphosphonic esters. | Sun, C. and Bittman, R. 2004. J Org Chem. 69: 7694-9. PMID: 15497998
- Translocation of sphingoid bases and their 1-phosphates, but not fumonisins, from roots to aerial tissues of maize seedlings watered with fumonisins. | Zitomer, NC., et al. 2010. J Agric Food Chem. 58: 7476-81. PMID: 20486705
- Maize seedling blight induced by Fusarium verticillioides: accumulation of fumonisin B₁ in leaves without colonization of the leaves. | Baldwin, TT., et al. 2014. J Agric Food Chem. 62: 2118-25. PMID: 24524621
- Aziridine ring opening for the synthesis of sphingolipid analogues: inhibitors of sphingolipid-metabolizing enzymes. | Alcaide, A. and Llebaria, A. 2014. J Org Chem. 79: 2993-3029. PMID: 24641332
- Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes. | Li, S., et al. 1999. J Lipid Res. 40: 117-25. PMID: 9869657
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
d-ribo Phytosphingosine 1-Phosphate, 1 mg | sc-207480 | 1 mg | $388.00 |