Molecular structure of D-NG-Nitroarginine Methyl Ester hydrochloride, CAS Number: 50912-92-0
D-NG-Nitroarginine Methyl Ester hydrochloride (CAS 50912-92-0)
See product citations (2)
Alternate Names:
D-Arg(NO2)-OMe hydrochloride
Application:
D-NG-Nitroarginine Methyl Ester hydrochloride is inactive stereoisomer of L-NAME NOS inhibitor
CAS Number:
50912-92-0
Purity:
98%
Molecular Weight:
269.69
Molecular Formula:
C7H15N5O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
D-NG-Nitroarginine Methyl Ester HCl (D-NAME) is the inactive stereoisomer of L-NAME (L-NG-Nitroarginine Methyl Ester HCl, sc-200333), itself a methyl ester derivative of the NOS (nitric oxide synthase) inhibitor L-NNA (N G-Nitro-L-arginine, sc-3570). L-NAME is hydrolyzed to L-NNA which then competes with L-arginine at the NOS arginine-binding site, blocking the arginine-dependent generation of NO by the enzyme. D-NAME is widely employed as a negative control for NOS inhibition studies with L-NAME.
D-NG-Nitroarginine Methyl Ester hydrochloride (CAS 50912-92-0) References
- Nitric oxide synthases: structure, function and inhibition. | Alderton, WK., et al. 2001. Biochem J. 357: 593-615. PMID: 11463332
- Intrahippocampal administration of the NO synthase inhibitor L-NAME prevents working memory deficits in rats exposed to transient cerebral ischemia. | Ohno, M., et al. 1994. Brain Res. 634: 173-7. PMID: 7512427
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-NG-Nitroarginine Methyl Ester hydrochloride, 250 mg | sc-200335 | 250 mg | $24.00 | |||
D-NG-Nitroarginine Methyl Ester hydrochloride, 1 g | sc-200335A | 1 g | $116.00 |