D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt)

D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) is a phosphorylated derivative of myo-inositol and a key player in cellular signal transduction. The compound contains four phosphate groups attached to the inositol ring at the 3, 4, 5, and 6 positions, making it an essential research tool for studying inositol phosphate signaling. Researchers utilize this tetraphosphate to explain the role of inositol phosphates in calcium signaling, intracellular trafficking, and metabolic regulation. One of its primary functions is regulating intracellular calcium levels. It achieves this by binding to specific receptors that influence calcium ion channels, impacting the release of calcium ions from internal stores. This mechanism affects various cellular processes like proliferation, differentiation, apoptosis, and cytoskeletal organization. Additionally, this compound is used to investigate phosphoinositide turnover and the activity of kinases and phosphatases involved in inositol phosphate metabolism. D-myo-Inositol-3,4,5,6-tetraphosphate is also instrumental in exploring the functional roles of phosphoinositides in cellular membranes. It binds with phosphoinositide-binding proteins, providing insights into the spatial-temporal regulation of signaling networks. Thus, this compound is vital for decoding the complex inositol phosphate-mediated signaling processes in cell physiology and contributes significantly to understanding intracellular signaling cascades.