Date published: 2025-11-4

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D-myo-Inositol-1,5-diphosphate, sodium salt

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Alternate Names:
Ins(1,5)-P2 (sodium salt); D- myo- inositol- 1, 5- di(hydrogen phosphate), disodium salt
Application:
D-myo-Inositol-1,5-diphosphate, sodium salt is a member of the inositol phosphate (InsP) molecular family
Purity:
>98%
Molecular Weight:
384.1
Molecular Formula:
C6H12O12P22Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-myo-Inositol-1,5-diphosphate, sodium salt, with phosphate groups attached at the 1 and 5 positions of the inositol ring, is part of the diverse group of inositol phosphate compounds that regulate crucial cellular signaling pathways. It is recognized for its relevance in phosphoinositide metabolism, offering researchers a valuable tool for studying intracellular signal transduction. The compound contributes to understanding how the phosphorylation state affects the behavior and function of inositol phosphates. Scientists utilize this compound to dissect the roles of specific phosphorylation patterns in phosphoinositide signaling cascades. In particular, studies have explored its contribution to the phosphatidylinositol cycle, where it′s essential in identifying how kinases and phosphatases regulate its presence. This research helps explain mechanisms underlying signal propagation related to cellular proliferation, differentiation, and stress responses. Moreover, D-myo-Inositol-1,5-diphosphate has been employed in studies investigating inositol phosphates′ influence on calcium mobilization, membrane dynamics, and protein-protein interactions. By providing a distinct phosphorylation pattern, it aids in revealing the specificity of receptor interactions and their downstream effects on various cellular compartments. Thus, it enhances our understanding of the roles of inositol phosphates in diverse cellular activities like metabolism, apoptosis, and immune responses.


D-myo-Inositol-1,5-diphosphate, sodium salt References

  1. Inositol phosphate biochemistry.  |  Majerus, PW. 1992. Annu Rev Biochem. 61: 225-50. PMID: 1323235
  2. Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate.  |  Streb, H., et al. Nature. 306: 67-9. PMID: 6605482
  3. Inositol trisphosphate and calcium signalling.  |  Berridge, MJ. 1993. Nature. 361: 315-25. PMID: 8381210
  4. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins.  |  Exton, JH. 1996. Annu Rev Pharmacol Toxicol. 36: 481-509. PMID: 8725399
  5. Structure and function of inositol 1,4,5-trisphosphate receptor.  |  Yoshida, Y. and Imai, S. 1997. Jpn J Pharmacol. 74: 125-37. PMID: 9243320

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-myo-Inositol-1,5-diphosphate, sodium salt, 100 µg

sc-223928
100 µg
$98.00

D-myo-Inositol-1,5-diphosphate, sodium salt, 500 µg

sc-223928A
500 µg
$444.00