D-myo-Inositol 1,4,5-trisphosphate triammonium salt (CAS 112571-69-4)

D-myo-Inositol 1,4,5-trisphosphate triammonium salt (D-InsP3) is a naturally occurring molecule found in numerous organisms, serving as a second messenger involved in diverse cellular processes. It plays a pivotal role in signal transduction, cellular growth and differentiation, as well as apoptosis. D-myo-Inositol 1,4,5-trisphosphate triammonium salt has been widely employed in diverse scientific research applications, spanning cell signaling, gene expression, apoptosis, and cell differentiation. It has proven invaluable in investigating the influence of intracellular calcium levels on cell proliferation and apoptosis, as well as exploring the regulatory role of D-myo-Inositol 1,4,5-trisphosphate triammonium salt in cell cycle progression. Additionally, it has played a key role in elucidating the involvement of G-proteins in signal transduction pathways. Acting as an intracellular messenger, D-myo-Inositol 1,4,5-trisphosphate triammonium salt binds to specific receptors located on the cell surface. This binding event initiates a series of intracellular processes, including the release of calcium from intracellular stores and the activation of calcium-dependent enzymes. The subsequent release of calcium triggers a cascade of events, ultimately resulting in the activation of secondary messenger molecules such as cyclic AMP (cAMP) and diacylglycerol (DAG). These secondary messengers, in turn, activate diverse intracellular pathways including MAPK, PI3K/Akt, and JAK/STAT, orchestrating various cellular responses.