D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt (CAS 102850-29-3)

D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt, a phosphate derivative of inositol, serves as a crucial signaling molecule in cellular processes and has garnered significant attention in scientific research, particularly in cell biology and molecular pharmacology. This compound functions as an important second messenger in intracellular signaling pathways, where it regulates diverse cellular functions such as cell growth, proliferation, and differentiation. Upon cellular stimulation, phospholipase C catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to generate inositol trisphosphate (IP3), which subsequently undergoes phosphorylation at the 1-position to form D-myo-Inositol 1,3,4,5-tetrakis(phosphate). This phosphorylated inositol compound plays pivotal roles in mediating calcium signaling and modulating the activity of downstream signaling molecules such as protein kinases and transcription factors. Researchers utilize D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt as a pharmacological tool to investigate the molecular mechanisms underlying intracellular signaling pathways and cellular responses to extracellular stimuli. Additionally, it serves as a valuable probe in studying the regulation of phosphoinositide signaling networks and the dynamics of intracellular calcium signaling. Furthermore, this compound finds applications in studying cell signaling cascades, cellular metabolism, and cellular communication processes in various physiological and pathological contexts. Its pivotal role in intracellular signaling and its applications in research make D-myo-Inositol 1,3,4,5-tetrakis(phosphate) ammonium salt an indispensable tool for advancing our understanding of cellular physiology and signaling mechanisms.