Molecular structure of D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt
Application:
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt is a soluble second messenger
Molecular Weight:
690.0
Molecular Formula:
C6H12O21P5•5Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphatase cycle, as well as with Ins(1,4,5,6)P4 in a 3-kinase/3-phosphatase cycle. Ins(1,3,4,5,6)P5 inhibits the phosphorylation and kinase activity of Akt/PKB, inducing apoptosis in ovarian, lung, and breast cancer cells. It displays antiangiogenic activity in vitro, blocking capillary tube formation of HUVEC, as well as antitumor effects against cancer xenografts in nude mices. Ins(1,3,4,5,6)P5 binds to the PH domain of Grp1.
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt References
- Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites. | McNamara, DE., et al. 2019. Cell Chem Biol. 26: 863-877.e7. PMID: 31031142
- Trait stacking simultaneously enhances provitamin A carotenoid and mineral bioaccessibility in biofortified Sorghum bicolor. | Dzakovich, MP., et al. 2023. Food Funct. 14: 7053-7065. PMID: 37449680
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt, 100 µg | sc-223921 | 100 µg | $100.00 | |||
D-myo-Inositol-1,3,4,5,6-pentaphosphate, sodium salt, 500 µg | sc-223921A | 500 µg | $294.00 |