D-myo-Inositol-1,2-diphosphate, sodium salt (CAS 208584-51-4)

D-myo-Inositol-1,2-diphosphate, sodium salt, features two phosphate groups attached to the 1 and 2 positions of the myo-inositol ring, representing a distinctive inositol phosphate compound. This particular configuration enables its involvement in phosphoinositide signaling pathways, where it can serve as a substrate or intermediate in various enzymatic reactions. It plays a role in studying intracellular signaling mechanisms and serves as a tool to investigate how phosphoinositide metabolism affects cellular processes. Research involving D-myo-Inositol-1,2-diphosphate often focuses on elucidating its specific enzyme-catalyzed formation and degradation pathways. By mapping the kinase and phosphatase activities that influence this compound′s phosphorylation state, scientists gain insights into the regulation of inositol phosphate-mediated signaling. It helps identify novel enzyme specificities, offering information on how phosphorylation patterns impact signal transduction. Moreover, the compound has been instrumental in exploring how different inositol phosphate isomers contribute to cellular activities, such as calcium mobilization, membrane trafficking, and cytoskeletal organization. The phosphorylation pattern at the 1 and 2 positions provides a useful system for studying receptor interactions and cellular compartmentalization of phosphoinositides. This work advances our understanding of inositol phosphate signaling and its regulatory roles in cell growth, metabolism, and differentiation.