D-myo-Inositol 1,2,5,6-tetrakisphosphate ammonium salt (CAS 91796-88-2)

D-myo-Inositol 1,2,5,6-tetrakisphosphate ammonium salt, a derivative of inositol phosphate, has garnered significant interest in biochemical research due to its crucial roles in cellular signaling and phosphate metabolism. This compound, characterized by phosphate groups at the 1, 2, 5, and 6 positions of the inositol ring, serves as a key intermediate in the phosphoinositide signaling cascade. Research has explaind its mechanism of action, wherein it functions as a substrate for various inositol phosphate kinases and phosphatases, contributing to the generation of important signaling molecules such as inositol pentakisphosphate (IP5) and inositol hexakisphosphate (IP6). Specifically, D-myo-Inositol 1,2,5,6-tetrakisphosphate ammonium salt has been implicated in regulating cellular processes such as calcium mobilization, vesicular trafficking, and gene expression. Furthermore, studies have highlighted its role in modulating ion channel activity, neurotransmitter release, and cytoskeletal dynamics, suggesting its importance in neuronal function and synaptic transmission. Additionally, this compound has been utilized as a molecular probe to dissect the intricacies of inositol phosphate signaling pathways and their implications in various physiological and pathological conditions. Its ability to modulate cellular responses to extracellular stimuli underscores its significance as a versatile research tool in the investigation of molecular mechanisms underlying cellular signaling and phosphate metabolism.