D-myo-Inositol-1,2,4,5-tetraphosphate, sodium salt

D-myo-Inositol-1,2,4,5-tetraphosphate, sodium salt is a phosphorylated derivative of inositol, specifically a tetraphosphate, which plays an important role in intracellular signaling pathways. As a second messenger, this inositol phosphate derivative interacts with proteins and enzymes that regulate crucial cellular processes, including calcium signaling and phosphate metabolism. The phosphorylation pattern of D-myo-Inositol-1,2,4,5-tetraphosphate (commonly abbreviated as IP4) makes it a critical intermediate in the phosphoinositide signaling pathway, which is pivotal in processes like cell growth, proliferation, and differentiation. In research, this compound has been utilized to investigate the regulation of phospholipase C and the production of downstream inositol phosphates like IP3 and IP6. Its unique structure allows it to bind selectively to signaling proteins involved in these pathways. Studies involving IP4 have helped explain how cells respond to extracellular stimuli and how alterations in inositol phosphate metabolism may affect signal transduction. Moreover, this compound aids in understanding the role of inositol phosphates in chromatin remodeling and transcriptional regulation, as it interacts with nuclear proteins. By analyzing its regulatory interactions, researchers have gained insights into nuclear signaling mechanisms that control gene expression and cellular adaptation. Thus, D-myo-Inositol-1,2,4,5-tetraphosphate remains vital for exploring the nuances of phosphoinositide-mediated cellular processes.