Date published: 2026-4-24

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D-Methionine (CAS 348-67-4)

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Alternate Names:
(R)-Methionine
CAS Number:
348-67-4
Purity:
≥99%
Molecular Weight:
149.21
Molecular Formula:
C5H11NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Methionine is an essential amino acid for a wide range of biochemical and physiological functions. It serves as a vital component of proteins and participates in the synthesis of other amino acids and hormones, as well as in the metabolism of fats and carbohydrates. Additionally, it is frequently used in research to examine the structure and function of proteins.


D-Methionine (CAS 348-67-4) References

  1. Biotransformation of D-methionine into L-methionine in the cascade of four enzymes.  |  Findrik, Z. and Vasić-Racki, D. 2007. Biotechnol Bioeng. 98: 956-67. PMID: 17534960
  2. D-methionine (D-met) significantly rescues noise-induced hearing loss: timing studies.  |  Campbell, K., et al. 2011. Hear Res. 282: 138-44. PMID: 21924333
  3. [D-methionine as a protector for irradiation-induced oral mucositis and xerostomia].  |  Yoshikawa, M. 2013. Nihon Yakurigaku Zasshi. 141: 310-3. PMID: 23749070
  4. D-methionine protects against cisplatin-induced neurotoxicity in the hippocampus of the adult rat.  |  Hinduja, S., et al. 2015. Neurotox Res. 27: 199-204. PMID: 25488710
  5. D-methionine (D-met) significantly reduces kanamycin-induced ototoxicity in pigmented guinea pigs.  |  Campbell, KC., et al. 2016. Int J Audiol. 55: 273-8. PMID: 26963517
  6. D-methionine interferes with non-typeable Haemophilus influenzae peptidoglycan synthesis during growth and biofilm formation.  |  Dawe, H., et al. 2017. Microbiology (Reading). 163: 1093-1104. PMID: 28699879
  7. D-methionine alleviates cisplatin-induced mucositis by restoring the gut microbiota structure and improving intestinal inflammation.  |  Wu, CH., et al. 2019. Ther Adv Med Oncol. 11: 1758835918821021. PMID: 30792823
  8. Effects of D-methionine in mice with noise-induced hearing loss mice.  |  Wang, Y., et al. 2019. J Int Med Res. 47: 3874-3885. PMID: 31327277
  9. D-methionine improves cisplatin-induced anorexia and dyspepsia syndrome by attenuating intestinal tryptophan hydroxylase 1 activity and increasing plasma leptin concentration.  |  Wong, YS., et al. 2020. Neurogastroenterol Motil. 32: e13803. PMID: 31989744
  10. d-Methionine and d-Phenylalanine Improve Lactococcus lactis F44 Acid Resistance and Nisin Yield by Governing Cell Wall Remodeling.  |  Wu, H., et al. 2020. Appl Environ Microbiol. 86: PMID: 32111594
  11. D-methionine immediate and continued rescue after noise exposure does not prevent temporary threshold shift but alters cochlear and serum antioxidant levels.  |  Campbell, KCM., et al. 2022. Int J Audiol. 61: 769-777. PMID: 34369249
  12. Effects of supplemental d-methionine in comparison to l-methionine on nitrogen retention, gut morphology, antioxidant status, and mRNA abundance of amino acid transporters in weanling pigs.  |  Espinosa, CD., et al. 2021. J Anim Sci. 99: PMID: 34432053
  13. D-methionine administered as late as 36 hours post-noise exposure rescues from permanent threshold shift and dose-dependently increases serum antioxidant levels.  |  Campbell, KCM., et al. 2023. Int J Audiol. 62: 151-158. PMID: 35015962
  14. D-Methionine and 2-hydroxy-4-methylthiobutanoic acid i alter beta-casein, proteins and metabolites linked in milk protein synthesis in bovine mammary epithelial cells.  |  Jeon, SW., et al. 2022. J Anim Sci Technol. 64: 481-499. PMID: 35709129
  15. D-methionine utilization in young miniature pigs, adult rabbits, and adult dogs.  |  Cho, ES., et al. 1980. JPEN J Parenter Enteral Nutr. 4: 544-7. PMID: 6780706

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Methionine, 5 g

sc-319872
5 g
$34.00

D-Methionine, 25 g

sc-319872A
25 g
$97.00