D-Mannosamine hydrochloride (CAS 5505-63-5)
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D-Mannosamine hydrochloride is a chemical used in various research fields, particularly in the study of glycosylation processes. As an analog of the naturally occurring monosaccharide mannosamine, it is incorporated into studies on the biosynthesis of sialic acid and its derivatives, which are for cell surface glycoproteins and glycolipids. Biochemists utilize D-Mannosamine hydrochloride to trace the pathways of sialic acid production and to elucidate the role of these sugars in cell-cell interactions, including in the immune response and pathogen recognition. The compound is also applied in the development of glycoconjugate materials for the exploration of glycan-mediated biological recognition and signaling. In addition, D-Mannosamine hydrochloride is used in the field of glycobiology to investigate the effects of altered glycosylation on protein function and stability, which can inform the design of novel biomaterials.
D-Mannosamine hydrochloride (CAS 5505-63-5) References
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- D-Mannosamine hydrochloride (2-amino-2-deoxy-D-mannose hydrochloride): ionic hydrogen bonding in saccharides involving chloride and aminium ions. | Lin, J., et al. 2022. Acta Crystallogr C Struct Chem. 78: 223-230. PMID: 35380125
- Haloacetamido analogues of 2-amino-2-deoxy-D-mannose. Syntheses and effects on tumor-bearing mice. | Fondy, TP. and Emlich, CA. 1981. J Med Chem. 24: 848-52. PMID: 7277392
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Mannosamine hydrochloride, 10 mg | sc-221500 | 10 mg | $23.00 | |||
D-Mannosamine hydrochloride, 100 mg | sc-221500A | 100 mg | $46.00 |