Molecular structure of D-Luciferin potassium salt, CAS Number: 115144-35-9
D-Luciferin potassium salt (CAS 115144-35-9)
Alternate Names:
(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid Monopotassium Salt; Firefly Potassium Salt
Application:
D-Luciferin potassium salt is a light-emitting heterocycle compounds found in organisms that cause bioluminescence, such as firefly
CAS Number:
115144-35-9
Purity:
≥95%
Molecular Weight:
318.41
Molecular Formula:
C11H7N2O3S2•K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Emitting a greenish-yellow glow when activated, D-Luciferin potassium salt is a heterocyclic, light-emitting natural ligand for luciferase. D-Luciferin potassium salt is a water-soluble version of D-Luciferin and a related analog to its sodium salt form, designed for use in chemiluminescence. It can also be dissolved in many buffers. When it undergoes oxidative decarboxylation in the presence of ATP and luciferase, D-Luciferin potassium salt emits light, serving as a bioluminescent indicator of ATP levels within various settings. D-Luciferin, a substrate for the enzyme firefly luciferase, is utilized in assays to monitor luciferase gene expression or to measure ATP concentration in cellular and biochemical assays.
D-Luciferin potassium salt (CAS 115144-35-9) References
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- Effects of sucrose and trehalose on stability, kinetic properties, and thermal aggregation of firefly luciferase. | Rasouli, S., et al. 2011. Appl Biochem Biotechnol. 165: 572-82. PMID: 21617898
- A novel mitotropic oligolysine nanocarrier: Targeted delivery of covalently bound D-Luciferin to cell mitochondria. | Theodossiou, TA., et al. 2011. Mitochondrion. 11: 982-6. PMID: 21856448
- Stereotactic intracranial implantation and in vivo bioluminescent imaging of tumor xenografts in a mouse model system of glioblastoma multiforme. | Baumann, BC., et al. 2012. J Vis Exp.. PMID: 23051742
- In vivo imaging of mice infected with bioluminescent Trypanosoma cruzi unveils novel sites of infection. | Henriques, C., et al. 2014. Parasit Vectors. 7: 89. PMID: 24589192
- Dual-color bioluminescence imaging assay using green- and red-emitting beetle luciferases at subcellular resolution. | Yasunaga, M., et al. 2014. Anal Bioanal Chem. 406: 5735-42. PMID: 25015042
- Bioluminescence-Based Tumor Quantification Method for Monitoring Tumor Progression and Treatment Effects in Mouse Lymphoma Models. | Cosette, J., et al. 2016. J Vis Exp.. PMID: 27501019
- Effect of β-elemene on the kinetics of intracellular transport of d-luciferin potassium salt (ABC substrate) in doxorubicin-resistant breast cancer cells and the associated molecular mechanism. | Tang, CY., et al. 2018. Eur J Pharm Sci. 120: 20-29. PMID: 29704644
- High Sensitivity In Vivo Imaging of Cancer Metastasis Using a Near-Infrared Luciferin Analogue seMpai. | Nakayama, J., et al. 2020. Int J Mol Sci. 21: PMID: 33114327
- Berberine Reverses Breast Cancer Multidrug Resistance Based on Fluorescence Pharmacokinetics In Vitro and In Vivo. | Qian, K., et al. 2021. ACS Omega. 6: 10645-10654. PMID: 34056218
- An in vivo orthotopic serial passaging model for a metastatic renal cancer study. | Nishida, J., et al. 2022. STAR Protoc. 3: 101306. PMID: 35496785
- Study on mechanism of elemene reversing tumor multidrug resistance based on luminescence pharmacokinetics in tumor cells in vitro and in vivo. | Chen, L., et al. 2020. RSC Adv. 10: 34928-34937. PMID: 35514396
- In Vivo Bioluminescent Imaging of Rabies Virus Infection and Evaluation of Antiviral Drug. | Yamada, K. and Nishizono, A. 2022. Methods Mol Biol. 2524: 347-352. PMID: 35821486
- Screening Multidrug Resistance Reversal Agents in Traditional Chinese Medicines by Efflux Kinetics of D-Luciferin in MCF-7/DOXFluc Cells. | Zhao, Y., et al. 2023. ACS Omega. 8: 4853-4861. PMID: 36777569
Activator of:
GPR35.Substrate of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Luciferin potassium salt, 50 mg | sc-278918 | 50 mg | $120.00 |