Date published: 2026-4-27

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D-Leucine amide (CAS 15893-47-7)

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Alternate Names:
D-Leu-NH2
CAS Number:
15893-47-7
Molecular Weight:
130.19
Molecular Formula:
C6H14N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Leucine amide is applied in biochemical chemistry, particularly in studies focusing on peptide structure and stability. D-Leucine Amide is instrumental in exploring the properties of peptides that incorporate D-amino acids, which can have implications for understanding protein folding and misfolding. In enzymology, D-Leucine amide serves as a substrate or inhibitor in assays designed to characterize the specificity and mechanism of action of peptidases and other enzymes that interact with D-amino acids. D-Leucine amide is utilized in the development of peptide-based materials, where the incorporation of D-amino acids can enhance stability against enzymatic degradation. D-Leucine amide is being studied in order to understand the role of D-amino acids in cellular signaling and neurological processes.


D-Leucine amide (CAS 15893-47-7) References

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  2. Purification, characterization, gene cloning and nucleotide sequencing of D: -stereospecific amino acid amidase from soil bacterium: Delftia acidovorans.  |  Hongpattarakere, T., et al. 2005. J Ind Microbiol Biotechnol. 32: 567-76. PMID: 15959727
  3. Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin.  |  Hanessian, S., et al. 2007. Bioorg Med Chem Lett. 17: 3480-5. PMID: 17428662
  4. New enzymatic method of chiral amino acid synthesis by dynamic kinetic resolution of amino acid amides: use of stereoselective amino acid amidases in the presence of alpha-amino-epsilon-caprolactam racemase.  |  Yamaguchi, S., et al. 2007. Appl Environ Microbiol. 73: 5370-3. PMID: 17586677
  5. alpha,alpha-Cyclic aminoacids as useful scaffolds for the preparation of hNK(2) receptor antagonists.  |  Sisto, A., et al. 2007. Bioorg Med Chem Lett. 17: 4841-4. PMID: 17604625
  6. A new D-stereospecific amino acid amidase from Ochrobactrum anthropi.  |  Asano, Y., et al. 1989. Biochem Biophys Res Commun. 162: 470-4. PMID: 2751665
  7. Properties of a novel D-stereospecific aminopeptidase from Ochrobactrum anthropi.  |  Asano, Y., et al. 1989. J Biol Chem. 264: 14233-9. PMID: 2760064
  8. Biocatalytic production of (S)-2-aminobutanamide by a novel d-aminopeptidase from Brucella sp. with high activity and enantioselectivity.  |  Tang, XL., et al. 2018. J Biotechnol. 266: 20-26. PMID: 29217400
  9. Microcystins Containing Doubly Homologated Tyrosine Residues from a Microcystis aeruginosa Bloom: Structures and Cytotoxicity.  |  He, H., et al. 2018. J Nat Prod. 81: 1368-1375. PMID: 29847132
  10. Bovine-lens leucine aminopeptidase. Kinetic studies with substrates and substrate-like inhibitors.  |  Fittkau, S., et al. 1974. Eur J Biochem. 44: 523-8. PMID: 4838681

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Leucine amide, 1 g

sc-285370
1 g
$66.00

D-Leucine amide, 5 g

sc-285370A
5 g
$275.00