Date published: 2026-1-20

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D,L-Venlafaxine-d6 (CAS 1020720-02-8)

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Alternate Names:
1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol-d6
Application:
D,L-Venlafaxine-d6 is a labeled selective serotonin noradrenaline reuptake inhibitor
CAS Number:
1020720-02-8
Purity:
≥98%
Molecular Weight:
283.44
Molecular Formula:
C17H21D6NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D,L-Venlafaxine-d6 is a deuterated derivative of venlafaxine, primarily utilized in research to investigate the metabolic pathways and pharmacokinetics of venlafaxine without the influence of metabolic isotopic effects. By incorporating deuterium, a stable isotope of hydrogen, into its molecular structure, D,L-Venlafaxine-d6 exhibits a higher resistance to enzymatic breakdown, which can provide clearer insights into how venlafaxine is metabolized in biological systems. This isotopic labeling also aids in the detection and quantification of the compound and its metabolites using mass spectrometry, thereby enhancing the accuracy of pharmacokinetic studies. As a racemic mixture, it encompasses both enantiomers, allowing for a comprehensive analysis of the stereochemical aspects of venlafaxine′s metabolism and interaction with various biological targets. The use of D,L-Venlafaxine-d6 in research applications helps in delineating the dynamics of venlafaxine′s biotransformation processes, contributing significantly to the understanding of its behavior in complex biological systems.


D,L-Venlafaxine-d6 (CAS 1020720-02-8) References

  1. Preparation of bovine serum albumin restricted access octadecyl/phenyl-mixed-functionalized magnetic silica nanoparticles for magnetic solid phase extraction of antidepressants in aquatic products followed by UHPLC-MS/MS.  |  Li, D., et al. 2021. Talanta. 221: 121458. PMID: 33076080
  2. Pharmaceuticals in edible crops irrigated with reclaimed wastewater: Evidence from a large survey in Israel.  |  Ben Mordechay, E., et al. 2021. J Hazard Mater. 416: 126184. PMID: 34492955
  3. Venlafaxine. A review of its pharmacology and therapeutic potential in depression.  |  Holliday, SM. and Benfield, P. 1995. Drugs. 49: 280-94. PMID: 7729333
  4. Venlafaxine: a new antidepressant drug.  |  Holdcroft, C. 1994. Nurse Pract. 19: 21. PMID: 7816367

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D,L-Venlafaxine-d6, 5 mg

sc-218060
5 mg
$406.00