Date published: 2025-11-1

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D,L-Trihexyphenidyl, Hydrochloride (CAS 58947-95-8)

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Application:
D,L-Trihexyphenidyl, Hydrochloride is an anticholinergic tertiary amine
CAS Number:
58947-95-8
Molecular Weight:
337.92
Molecular Formula:
C20H31NO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D,L-Trihexyphenidyl, Hydrochloride functions as an antagonist of muscarinic acetylcholine receptors. It acts by competitively inhibiting the action of acetylcholine at its receptor sites, thereby blocking the excitatory effects of the neurotransmitter in the central nervous system. Its ability to modulate cholinergic neurotransmission provides researchers with a means to study the physiological and behavioral effects of disrupting this signaling pathway, contributing to a better understanding of the underlying mechanisms involved.


D,L-Trihexyphenidyl, Hydrochloride (CAS 58947-95-8) References

  1. Rat hippocampal muscarinic autoreceptors are similar to the M2 (cardiac) subtype: comparison with hippocampal M1, atrial M2 and ileal M3 receptors.  |  Richards, MH. 1990. Br J Pharmacol. 99: 753-61. PMID: 1694463
  2. A multiplex calcium assay for identification of GPCR agonists and antagonists.  |  Liu, K., et al. 2010. Assay Drug Dev Technol. 8: 367-79. PMID: 20230302
  3. Cholinergic manipulation of motor disability and L-DOPA-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated common marmosets.  |  Jackson, MJ., et al. 2014. J Neural Transm (Vienna). 121: 163-9. PMID: 23959162

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D,L-Trihexyphenidyl, Hydrochloride, 5 g

sc-211201
5 g
$240.00