D,L-Sulforaphane-d8 (CAS 836682-32-7)

D,L-Sulforaphane-d8, an isotopically labeled variant of sulforaphane, serves a pivotal role in molecular biology research, particularly in the study of cellular defense mechanisms against oxidative stress and electrophilic damage. This compound is utilized for its ability to reliably trace and analyze the biochemical pathways and metabolic processes of sulforaphane due to the inclusion of eight deuterium atoms, which are heavier isotopes of hydrogen. This modification enhances its detection and quantification using mass spectrometry, making it an invaluable tool in experiments that require precise tracking of molecular transformations. Researchers leverage D,L-Sulforaphane-d8 to explore its modulation of the Nrf2 pathway, a critical cellular defense pathway against environmental stressors, offering insights into the underlying mechanisms that cells use to regulate oxidative stress and maintain homeostasis. Its use in research extends to examining how such compounds influence gene expression and protein function, contributing significantly to the understanding of cellular resilience and adaptation.