Molecular structure of D,L-3-Indolylglycine, CAS Number: 6747-15-5
D,L-3-Indolylglycine (CAS 6747-15-5)
Application:
D,L-3-Indolylglycine is an unnatural amino acid with an α-indole substitution
CAS Number:
6747-15-5
Molecular Weight:
190.20
Molecular Formula:
C10H10N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D,L-3-Indolylglycine is an unnatural amino acid that is very similar to Tryptophan (sc-280888), with the indole moiety directly attached to the α-position. D,L-3-Indolylglycine may be useful in the design of functional proteins. A study describes the inclusion of a similar aza-indoylglycine moiety in petidomimetics with the purpose of functionally replacing tryptophan moieties.
D,L-3-Indolylglycine (CAS 6747-15-5) References
- Copper-catalyzed N-arylation of semicarbazones for the synthesis of aza-arylglycine-containing aza-peptides. | Proulx, C. and Lubell, WD. 2010. Org Lett. 12: 2916-9. PMID: 20536163
- Synthesis of optically active 2- and 3- indolylglycine derivatives and their oxygen analogues. | Goswami, K., et al. 2012. J Org Chem. 77: 7081-5. PMID: 22834412
- Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(II) complex and indoles. | Lin, D., et al. 2013. Chem Commun (Camb). 49: 2575-7. PMID: 23423386
- Amino acidic scaffolds bearing unnatural side chains: an old idea generates new and versatile tools for the life sciences. | Stevenazzi, A., et al. 2014. Bioorg Med Chem Lett. 24: 5349-56. PMID: 25455481
- Pseudellones A-C, Three Alkaloids from the Marine-Derived Fungus Pseudallescheria ellipsoidea F42-3. | Liu, W., et al. 2015. Org Lett. 17: 5156-9. PMID: 26452138
- Synthesis of 3-Indolylglycine Derivatives via Dinuclear Zinc Catalytic Asymmetric Friedel-Crafts Alkylation Reaction. | Wang, XW., et al. 2016. J Org Chem. 81: 9227-9234. PMID: 27626632
- Natural Products Research in China From 2015 to 2016. | Liu, H., et al. 2018. Front Chem. 6: 45. PMID: 29616210
- Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon. | Benfodda, Z., et al. 2018. Amino Acids. 50: 1307-1328. PMID: 30099594
- Marine-derived fungi as a source of bioactive indole alkaloids with diversified structures. | Meng, ZH., et al. 2021. Mar Life Sci Technol. 3: 44-61. PMID: 37073395
- Dinuclear Zn-Catalytic System as Brønsted Base and Lewis Acid for Enantioselectivity in Same Chiral Environment. | Ayesha, ., et al. 2024. ACS Omega. 9: 6074-6092. PMID: 38375498
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D,L-3-Indolylglycine, 100 mg | sc-211191 | 100 mg | $330.00 |