Date published: 2025-10-20

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D-Gulose (CAS 4205-23-6)

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Application:
D-Gulose is a aldohexose sugar that is very rare in nature but has been found in archaea, bacteria and other eukaryotes
CAS Number:
4205-23-6
Purity:
≥99%
Molecular Weight:
180.16
Molecular Formula:
C6H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Gulose is a aldohexose sugar that is very rare in nature but has been found in archaea, bacteria, and other eukaryotes. It is a less studied monosaccharide compared to more prevalent sugars like glucose, fructose, or even D-Ribose. However, researchers have explored and used D-Gulose in various ways for specific purposes. Some of the potential applications and uses of D-Gulose in research include metabolic studies, enzyme studies, glycosylation studies, chemical synthesis and modification, biosynthesis pathways, analytical techniques, and biotechnology and microbial engineering.


D-Gulose (CAS 4205-23-6) References

  1. Ligand recognition by the lactose permease of Escherichia coli: specificity and affinity are defined by distinct structural elements of galactopyranosides.  |  Sahin-Tóth, M., et al. 2000. Biochemistry. 39: 5097-103. PMID: 10819976
  2. Biosynthesis of D- and L-glycero-L-galacto-octulose from pentoses and hexoses.  |  Haustveit, G., et al. 1975. Carbohydr Res. 39: 125-9. PMID: 1111959
  3. Acyclic forms of [1-(13)C]aldohexoses in aqueous solution: quantitation by (13)C NMR and deuterium isotope effects on tautomeric equilibria.  |  Zhu, Y., et al. 2001. J Org Chem. 66: 6244-51. PMID: 11559169
  4. Preparation of L-talose and D-gulose from L-tagatose and D-sorbose, respectively, using immobilized L-rhamnose isomerase.  |  Bhuiyan, SH., et al. 1999. J Biosci Bioeng. 88: 567-70. PMID: 16232663
  5. Identification, isolation, and structural studies of extracellular polysaccharides produced by Caulobacter crescentus.  |  Ravenscroft, N., et al. 1991. J Bacteriol. 173: 5677-84. PMID: 1885545
  6. Substrate specificity of ribose-5-phosphate isomerases from Clostridium difficile and Thermotoga maritima.  |  Yeom, SJ., et al. 2010. Biotechnol Lett. 32: 829-35. PMID: 20155483
  7. Preparation of D-gulose from disaccharide lactitol using microbial and chemical methods.  |  Morimoto, K., et al. 2013. Biosci Biotechnol Biochem. 77: 253-8. PMID: 23391912
  8. L-Rhamnose isomerase and its use for biotechnological production of rare sugars.  |  Xu, W., et al. 2016. Appl Microbiol Biotechnol. 100: 2985-92. PMID: 26875877
  9. Acyclic forms of aldohexoses and ketohexoses in aqueous and DMSO solutions: conformational features studied using molecular dynamics simulations.  |  Plazinski, W., et al. 2016. Phys Chem Chem Phys. 18: 9626-35. PMID: 26996921
  10. Triacetonide of Glucoheptonic Acid in the Scalable Syntheses of d-Gulose, 6-Deoxy-d-gulose, l-Glucose, 6-Deoxy-l-glucose, and Related Sugars.  |  Liu, Z., et al. 2016. Org Lett. 18: 4112-5. PMID: 27487167
  11. Metabolic engineering pathways for rare sugars biosynthesis, physiological functionalities, and applications-a review.  |  Bilal, M., et al. 2018. Crit Rev Food Sci Nutr. 58: 2768-2778. PMID: 28662355
  12. Cloning and expression of d-glucoside 3-dehydrogenase from Rhizobium sp. S10 in Escherichia coli and its application for d-gulose production.  |  Yotsombat, A., et al. 2019. Protein Expr Purif. 156: 58-65. PMID: 30629972
  13. Functional Characterization of the ycjQRS Gene Cluster from Escherichia coli: A Novel Pathway for the Transformation of d-Gulosides to d-Glucosides.  |  Mukherjee, K., et al. 2019. Biochemistry. 58: 1388-1399. PMID: 30742415
  14. A gulose moiety contributes to the belomycin (BLM) disaccharide selective targeting to lung cancer cells.  |  Zhou, C., et al. 2021. Eur J Med Chem. 226: 113866. PMID: 34619466

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Gulose, 50 mg

sc-285364
50 mg
$199.00

D-Gulose, 100 mg

sc-285364A
100 mg
$311.00