Molecular structure of D-Glucosamine 6-phosphate, CAS Number: 3616-42-0
D-Glucosamine 6-phosphate (CAS 3616-42-0)
Alternate Names:
(5-amino-2,3,4-trihydroxy-6-oxohexyl) dihydrogen phosphate
Application:
D-Glucosamine 6-phosphate is for glucose metabolism studies
CAS Number:
3616-42-0
Purity:
≥98%
Molecular Weight:
259.15
Molecular Formula:
C6H14NO8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
D-Glucosamine 6-phosphate is a biochemical compound involved in amino sugar metabolism and protein glycosylation studies. As an integral intermediate in the hexosamine biosynthesis pathway, it is pivotal for the synthesis of various biomolecules, including glycosaminoglycans and glycoproteins. Within research applications, its role is further examined for its influence on cellular signaling and glucose metabolism regulation. This compound′s phosphorylation state is key to enzymatic activity, influencing the production of N-acetylglucosamine-6-phosphate and subsequent biologically relevant molecules. Investigations into D-Glucosamine 6-phosphate not only shed light on normal cellular functions but also on metabolic disruptions, offering a deeper understanding of disease mechanisms.
D-Glucosamine 6-phosphate (CAS 3616-42-0) References
- Inhibition of Escherichia coli glucosamine-6-phosphate synthase by reactive intermediate analogues. The role of the 2-amino function in catalysis. | Bearne, SL. and Blouin, C. 2000. J Biol Chem. 275: 135-40. PMID: 10617596
- Hydrophobic derivatives of 2-amino-2-deoxy-D-glucitol-6-phosphate: a new type of D-glucosamine-6-phosphate synthase inhibitors with antifungal action. | Janiak, AM., et al. 2003. Bioorg Med Chem. 11: 1653-62. PMID: 12659751
- Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study. | Arreola, R., et al. 2003. FEBS Lett. 551: 63-70. PMID: 12965206
- Action of phosphoglucomutase on D-glucosamine-6-phosphate. | BROWN, DH. 1953. J Biol Chem. 204: 877-89. PMID: 13117866
- Specificity of nucleotide sequence in DNA cleavage induced by D-glucosamine and D-glucosamine-6-phosphate in the presence of Cu2+. | Watanabe, K., et al. 1990. Agric Biol Chem. 54: 519-25. PMID: 1369256
- Purification and characterization of glucosamine-6-phosphate deaminase from dog kidney cortex. | Lara-Lemus, R., et al. 1992. Arch Biochem Biophys. 297: 213-20. PMID: 1497340
- Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase. | Milewski, S., et al. 2006. Arch Biochem Biophys. 450: 39-49. PMID: 16631105
- Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase. | Hall, RS., et al. 2007. Biochemistry. 46: 7953-62. PMID: 17567048
- An enzyme-coupled assay for amidotransferase activity of glucosamine-6-phosphate synthase. | Li, Y., et al. 2007. Anal Biochem. 370: 142-6. PMID: 17880906
- Ordering of C-terminal loop and glutaminase domains of glucosamine-6-phosphate synthase promotes sugar ring opening and formation of the ammonia channel. | Mouilleron, S., et al. 2008. J Mol Biol. 377: 1174-85. PMID: 18295797
- Formation of glucosamine 6-phosphate in regenerating rat liver. | Akamatsu, N. and Maeda, HR. 1971. Biochim Biophys Acta. 244: 311-7. PMID: 5125613
- Inactivation and resynthesis of glucosamine-6-phosphate synthetase after treatment with glutamine analogs. | Bates, CJ. and Handschumacher, RE. 1969. Adv Enzyme Regul. 7: 183-204. PMID: 5367804
- Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution. | Oliva, G., et al. 1995. Structure. 3: 1323-32. PMID: 8747459
- Antibacterial action of dipeptides containing an inhibitor of glucosamine-6-phosphate isomerase. | Chmara, H., et al. 1998. Microbiology (Reading). 144 (Pt 5): 1349-1358. PMID: 9660640
- Cloning of two putative Giardia lamblia glucosamine 6-phosphate isomerase genes only one of which is transcriptionally activated during encystment. | Van Keulen, H., et al. 1998. J Eukaryot Microbiol. 45: 637-42. PMID: 9864853
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Glucosamine 6-phosphate, 10 mg | sc-214809 | 10 mg | $51.00 | |||
D-Glucosamine 6-phosphate, 100 mg | sc-214809A | 100 mg | $143.00 | |||
D-Glucosamine 6-phosphate, 500 mg | sc-214809B | 500 mg | $439.00 | |||
D-Glucosamine 6-phosphate, 1 g | sc-214809C | 1 g | $806.00 |