Date published: 2025-12-19

1-800-457-3801

SCBT Portrait Logo
Seach Input

D-Glucamine (CAS 488-43-7)

0.0(0)
Write a reviewAsk a question

Alternate Names:
1-Amino-1-deoxy-D-glucitol
CAS Number:
488-43-7
Purity:
≥97%
Molecular Weight:
181.19
Molecular Formula:
C6H15NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

D-Glucamine, also known as glucosamine, plays a crucial role in various research fields, particularly in biochemistry, pharmacology, and nutrition. It serves as a precursor for the biosynthesis of glycosaminoglycans, which are essential components of connective tissues such as cartilage, tendons, and ligaments. Glucosamine is involved in the production of proteoglycans, which are crucial for maintaining the structural integrity and elasticity of these tissues. Research indicates that glucosamine supplementation can stimulate the synthesis of glycosaminoglycans in chondrocytes, the cells responsible for cartilage formation, thereby promoting cartilage repair and potentially alleviating symptoms of osteoarthritis. Additionally, glucosamine has been studied for its anti-inflammatory properties, which may contribute to its beneficial effects in joint health. Beyond its role in musculoskeletal health, glucosamine has also been investigated for its potential in modulating cellular signaling pathways, such as the mTOR pathway, and its involvement in glucose metabolism. Furthermore, research suggests that glucosamine may have applications in promoting gut health and supporting the integrity of the intestinal barrier. Overall, D-Glucamine holds promise as a versatile compound with diverse research applications spanning from musculoskeletal health to cellular signaling and metabolic regulation.


D-Glucamine (CAS 488-43-7) References

  1. Synthesis and biological evaluation of ureido and thioureido derivatives of 2-amino-2-deoxy-D-glucose and related aminoalcohols as N-acetyl-beta-D-hexosaminidase inhibitors.  |  Tournaire-Arellano, C., et al. 1998. Carbohydr Res. 314: 47-63. PMID: 10230037
  2. Perfluoroalkylated derivatives of 6-deoxy-6-ethylamino-D-galactose, 1-deoxy-1-methylamino-D-glucitol, and 1-amino-1-deoxy-D-glucitol: syntheses, hemocompatibility, and effect on perfluorocarbon emulsion.  |  Kaplánek, R., et al. 2010. Carbohydr Res. 345: 1008-14. PMID: 20382375
  3. Electronic effects in tautomeric equilibria: the case of chiral imines from d-glucamine and 2-hydroxyacetophenones.  |  Matamoros, E., et al. 2019. Org Biomol Chem. 17: 10209-10222. PMID: 31774417
  4. Schiff Bases and Stereocontrolled Formation of Fused 1,3-Oxazolidines from 1-Amino-2-Indanol: A Systematic Study on Structure and Mechanism.  |  Matamoros, E., et al. 2023. Molecules. 28: PMID: 36838659
  5. Synthesis of the 1-amino-alditols derived from cellobiose, lactose and maltose. A comprehensive NMR study of some alditols and amino-alditols  |  Christiansen-Brams, I., Meldal, M., & Bock, K. 1992. Journal of carbohydrate chemistry. 11(7): 813-835.
  6. O-Acetyl protection of 6-aminoaldopyranosides and 1-aminoalditols  |  Mellet, C. O., Jiménez Bianco, J. L., García Fernández, J. M., & Fuentes, J. 1995. Carbohydrate Chemistry. 14(8): 1133-1152.
  7. Electrosynthesis of oligosaccharide glycamines  |  Fedoroňko, M., Stach, T., Capek, P., & Farkaš, V. 1998. Carbohydrate research. 306(3): 457-461.
  8. The synthesis of 6-azido and 6-amino analogues of 1-deoxynojirimycin and their conversion to bicyclic derivatives  |  Kilonda, A., Compernolle, F., Peeters, K., Joly, G. J., Toppet, S., & Hoornaert, G. J. 2000. Tetrahedron. 56(7): 1005-1012.
  9. Synthesis of 1-deoxymannojirimycin analogues using N-tosyl and N-nosyl activated aziridines derived from 1-amino-1-deoxyglucitol  |  Mao, H., Joly, G. J., Peeters, K., Hoornaert, G. J., & Compernolle, F. 2001. Tetrahedron. 57(32): 6955-6967.
  10. Molecular dynamics study on the influence of C-terminal sugar substitution on dynamics and conformation of vancomycin derivatives  |  Ślusarz, R., Samaszko-Fiertek, J., Dmochowska, B., & Madaj, J. 2017. Journal of Carbohydrate Chemistry. 36(1): 45-58.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Glucamine, 1 g

sc-221481
1 g
$210.00

D-Glucamine, 5 g

sc-221481A
5 g
$460.00

D-Glucamine, 25 g

sc-221481B
25 g
$800.00