Date published: 2026-9-1

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D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt (CAS 103213-44-1)

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Alternate Names:
D(+)Fructofuranose 1,6-diphosphate; Harden-Young ester; Hexose diphosphate
CAS Number:
103213-44-1
Purity:
≥95%
Molecular Weight:
736.81
Molecular Formula:
C30H66N4O12P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt (CAS: 103213-44-1) is a modified form of fructose 1,6-bisphosphate, a key intermediate in the glycolysis pathway. This salt is frequently employed in biochemical and enzymatic studies due to its stability and solubility properties conferred by the cyclohexylammonium groups. In research, one of the primary applications of this compound is its utilization as a substrate or activator in studies involving enzymes related to carbohydrate metabolism. Specifically, it serves as a potent activator of the enzyme pyruvate kinase, a key regulatory enzyme in glycolysis that catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate, coupled with the production of ATP. By studying the interaction between D-fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt and pyruvate kinase, researchers gain insights into the regulation of glycolytic flux and energy metabolism in various biological systems. Furthermore, this compound is also utilized in investigations focusing on the allosteric regulation of other enzymes involved in glucose metabolism, shedding light on the complex network of metabolic pathways and their control mechanisms. Overall, the research applications of D-fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt contribute to advancing our understanding of fundamental cellular processes and metabolic regulation, offering potential insights into metabolic disorders and energy-related diseases.


D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt (CAS 103213-44-1) References

  1. Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.  |  Pegan, SD., et al. 2013. Biochemistry. 52: 912-25. PMID: 23298222
  2. A noncompetitive inhibitor for Mycobacterium tuberculosis's class IIa fructose 1,6-bisphosphate aldolase.  |  Capodagli, GC., et al. 2014. Biochemistry. 53: 202-13. PMID: 24325645
  3. Conserved residues of the Pro103-Arg115 loop are involved in triggering the allosteric response of the Escherichia coli ADP-glucose pyrophosphorylase.  |  Hill, BL., et al. 2015. Protein Sci. 24: 714-28. PMID: 25620658
  4. GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii.  |  Martin, JH., et al. 2018. J Bacteriol. 200: PMID: 29914986

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt, 5 g

sc-214804
5 g
$156.00

D-Fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt, 10 g

sc-214804A
10 g
$311.00