Date published: 2026-2-8

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D-erythro-Sphingosine C-15 (CAS 86555-28-4)

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Application:
D-erythro-Sphingosine C-15 is a naturally-occurring but rare form of sphingosine
CAS Number:
86555-28-4
Purity:
≥98%
Molecular Weight:
257.4
Molecular Formula:
C15H31NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-erythro-Sphingosine C-15, a synthetic sphingolipid variant, is distinguished by its fifteen-carbon fatty acyl chain and forms a key component of research into the structural and functional roles of sphingolipids in cellular processes. This molecule adopts the D-erythro configuration, closely mimicking the naturally occurring stereochemistry of sphingosines, which is crucial for its biological relevance and interaction with cellular components. Its structure allows it to easily integrate into cellular membranes, affecting their properties such as fluidity, thickness, and the formation of specialized lipid domains. In research, D-erythro-Sphingosine C-15 is particularly valuable for studying the dynamics of sphingolipids within membranes and their impact on signal transduction pathways. Its unique length influences the curvature and microenvironment of lipid bilayers, offering insights into how variations in lipid tail length can affect membrane behavior and protein interactions. This compound is instrumental in probing the mechanisms through which sphingosines modulate cellular signaling networks involved in regulating cell growth, differentiation, and response to external stimuli. By utilizing D-erythro-Sphingosine C-15 in experimental models, researchers can explain the complex roles of sphingolipids in cellular physiology and their potential impact on cellular signaling landscapes.


D-erythro-Sphingosine C-15 (CAS 86555-28-4) References

  1. Biodiversity of sphingoid bases ('sphingosines') and related amino alcohols.  |  Pruett, ST., et al. 2008. J Lipid Res. 49: 1621-39. PMID: 18499644
  2. Red blood cell metabolism under prolonged anaerobic storage.  |  D'Alessandro, A., et al. 2013. Mol Biosyst. 9: 1196-209. PMID: 23426130
  3. Metabolomics Profiling Discriminates Prostate Cancer From Benign Prostatic Hyperplasia Within the Prostate-Specific Antigen Gray Zone.  |  Xu, B., et al. 2021. Front Oncol. 11: 730638. PMID: 34722271
  4. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines.  |  Stewart, ME. and Downing, DT. 1995. J Invest Dermatol. 105: 613-8. PMID: 7561168
  5. Red blood cell lipidomics analysis through HPLC-ESI-qTOF: application to red blood cell storage  |  Timperio, A. M., Mirasole, C., D'Alessandro, A., & Zolla, L. 2013. Journal of Integrated OMICS. 3(1): 11-24.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-erythro-Sphingosine C-15, 1 mg

sc-358749
1 mg
$100.00

D-erythro-Sphingosine C-15, 5 mg

sc-358749A
5 mg
$395.00