D-Dimer Antibody (DD3): sc-51862

D-Dimer Antibody (DD3) is a mouse monoclonal IgG2b antibody that detects the D-Dimer protein of human origin by western blotting (WB) and immunoprecipitation (IP). Anti-D-Dimer antibody (DD3) is available as the non-conjugated format, providing a reliable tool for researchers studying coagulation processes. D-Dimer, a critical biomarker in the assessment of thrombotic disorders, is generated during the degradation of fibrin, which is a key component of blood clots. D-Dimer protein is formed from the cleavage of fibrin by plasmin, resulting in fragments that are released into the bloodstream. D-Dimer consists of specific amino acid sequences derived from the α, β, and γ chains of fibrinogen, with the dimeric structure stabilized by disulfide and isopeptide bonds. Measurement of D-Dimer levels in plasma and whole blood is particularly important in clinical settings, as elevated levels can indicate the presence of venous thromboembolism, making D-Dimer monoclonal antibody (DD3) an essential tool for both diagnostic and research applications in understanding coagulation and its disorders.

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D-Dimer Antibody (DD3) References:

1. Fibrin fragment D-dimer and the risk of future venous thrombosis.  |  Cushman, M., et al. 2003. Blood. 101: 1243-8. PMID: 12393393
2. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis.  |  Wells, PS., et al. 2003. N Engl J Med. 349: 1227-35. PMID: 14507948
3. D-dimer levels correlate with mortality in patients with acute pulmonary embolism: Findings from the RIETE registry.  |  Grau, E., et al. 2007. Crit Care Med. 35: 1937-41. PMID: 17581488
4. Blood chemistry measurements and D-Dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus.  |  Rollin, PE., et al. 2007. J Infect Dis. 196 Suppl 2: S364-71. PMID: 17940972
5. The value of the D-Dimer assay for predicting vein thrombosis in rehabilitation patients receiving prophylactic low molecular weight heparin doses.  |  Formisano, R., et al. 2007. Brain Inj. 21: 1419-24. PMID: 18066944
6. Measurement of crosslinked fibrin derivatives--use in the diagnosis of venous thrombosis.  |  Rowbotham, BJ., et al. 1987. Thromb Haemost. 57: 59-61. PMID: 3590082
7. Plasma measurement of D-dimer as diagnostic aid in suspected venous thromboembolism: an overview.  |  Bounameaux, H., et al. 1994. Thromb Haemost. 71: 1-6. PMID: 8165626
8. A comparative analysis of D-dimer assays in patients with clinically suspected pulmonary embolism.  |  van Beek, EJ., et al. 1993. Thromb Haemost. 70: 408-13. PMID: 8259539
9. Plasma fibrinogen and fibrin D-dimer in patients with atrial fibrillation: effects of cardioversion to sinus rhythm.  |  Lip, GY., et al. 1995. Int J Cardiol. 51: 245-51. PMID: 8586473

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-D-Dimer Antibody (DD3) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-D-Dimer Antibody (DD3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

D-Dimer Antibody (DD3) Specifications

Alternate Product Name: D-Dimer

Product Clone Name: DD3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b

Amino Acids:

Epitope Target: D-Dimer

Epitope Species: human

Product Reactivity/Detection: D-Dimer

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG_2b in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for D-Dimer Antibody (DD3): N/A