D-Desthiobiotin (CAS 533-48-2)
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D-Desthiobiotin is a biotin analog that has a high affinity for streptavidin and avidin, similar to biotin itself, but with a key structural difference that allows for its reversible binding. It is a valuable compound in biochemical research for affinity chromatography, where it is used to purify proteins that have been tagged with streptavidin or avidin. This reversible interaction is particularly useful in the gentle elution of captured proteins under mild conditions, preserving their activity. Additionally, D-Desthiobiotin is employed in the study of protein-protein interactions, leveraging the strong non-covalent binding of biotin and its analogs to streptavidin for immobilization on various surfaces or beads. Researchers also use it in the development of detection assays, where the binding and release of D-Desthiobiotin-tagged molecules can be dynamically controlled, facilitating the quantitative analysis of various biomolecules.
D-Desthiobiotin (CAS 533-48-2) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Desthiobiotin, 500 mg | sc-294239 | 500 mg | $200.00 | |||
D-Desthiobiotin, 1 g | sc-294239A | 1 g | $341.00 |