Date published: 2026-5-9

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D-Citrulline (CAS 13594-51-9)

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Alternate Names:
(R)-2-Amino-5-ureidopentanoic acid
CAS Number:
13594-51-9
Purity:
≥95%
Molecular Weight:
175.19
Molecular Formula:
C6H13N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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D-Citrulline, a naturally occurring amino acid,. It is categorized as a non-essential amino acid.meaning it can be produced by the body and participates in various biochemical processes. In scientific research, D-Citrulline has been extensively employed. Experimentation in laboratory applications where it has demonstrated advantageous properties. Mechanistically, D-Citrulline functions in multiple ways. It plays a vital role in the urea cycle, responsible for eliminating ammonia from the bloodstream. Additionally, it acts as an antioxidant, safeguarding the body against oxidative damage.


D-Citrulline (CAS 13594-51-9) References

  1. L-citrulline recycling by argininosuccinate synthetase and lyase in rat gastric fundus.  |  Van Geldre, LA., et al. 2002. Eur J Pharmacol. 455: 149-60. PMID: 12445581
  2. Preparation of D-ornithine, D-citrulline, and D-arginine.  |  LEVINTOW, L. and GREENSTEIN, JP. 1951. J Biol Chem. 188: 643-6. PMID: 14824152
  3. On leaking into the lumen, amino acids cross the tubule cells. Secretion of L-citrulline in the isolated-perfused non-filtering kidney of the African clawed toad (Xenopus laevis).  |  Gekle, M. and Silbernagl, S. 1991. Pflugers Arch. 419: 499-503. PMID: 1775372
  4. A Simple Enzymatic Method for Production of a Wide Variety of D-Amino Acids Using L-Amino Acid Oxidase from Rhodococcus sp. AIU Z-35-1.  |  Isobe, K., et al. 2010. Enzyme Res. 2010: 567210. PMID: 21048866
  5. Lipodiscamides A-C, new cytotoxic lipopeptides from Discodermia kiiensis.  |  Tan, KC., et al. 2014. Org Lett. 16: 3256-9. PMID: 24906171
  6. Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.  |  Koga, R., et al. 2017. Front Mol Biosci. 4: 82. PMID: 29255714
  7. Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.  |  Trier, NH., et al. 2019. Antibodies (Basel). 8: PMID: 31544843
  8. Highly potent antagonists of luteinizing hormone-releasing hormone free of edematogenic effects.  |  Bajusz, S., et al. 1988. Proc Natl Acad Sci U S A. 85: 1637-41. PMID: 3278323
  9. A Conserved Nonribosomal Peptide Synthetase in Xenorhabdus bovienii Produces Citrulline-Functionalized Lipopeptides.  |  Li, JH., et al. 2021. J Nat Prod. 84: 2692-2699. PMID: 34581573
  10. Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75.  |  Yano, T., et al. 1994. Proc Natl Acad Sci U S A. 91: 7090-4. PMID: 7518926
  11. Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.  |  Lee, TJ., et al. 1996. J Pharmacol Exp Ther. 276: 353-8. PMID: 8632296
  12. L-citrulline conversion to L-arginine in sphenopalatine ganglia and cerebral perivascular nerves in the pig.  |  Yu, JG., et al. 1997. Am J Physiol. 273: H2192-9. PMID: 9374753

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

D-Citrulline, 1 g

sc-255053
1 g
$169.00